Assessing prognostic significance of preoperative alpha-fetoprotein in hepatitis B-associated hepatocellular carcinoma: normal is not the new normal

S Blank, Q Wang, MI Fiel, W Luan, KW Kim… - Annals of surgical …, 2014 - Springer
Abstract Background Hepatitis B (HBV)-associated hepatocellular carcinoma (HCC) is often
associated with alpha-fetoprotein (AFP) production. Although serum AFP has been …

[HTML][HTML] The dynamic changes of AFP from baseline to recurrence as an excellent prognostic factor of hepatocellular carcinoma after locoregional therapy: a 5-year …

Q Wang, B Liu, W Qiao, J Li, C Yuan, J Long… - Frontiers in …, 2021 - frontiersin.org
Background: Although many studies have confirmed the prognostic value of preoperative
alpha-fetoprotein (AFP) in patients with hepatocellular carcinoma (HCC), no one study has …

[HTML][HTML] Is inconsistency of α-fetoprotein level a good prognosticator for hepatocellular carcinoma recurrence?

CB Hsieh, TW Chen, CM Chu, HC Chu… - World Journal of …, 2010 - ncbi.nlm.nih.gov
AIM: To identify the clinical outcomes of hepatocellular carcinoma (HCC) patients with
inconsistent α-fetoprotein (AFP) levels which were initially high and then low at recurrence …

[HTML][HTML] Preoperative alpha-fetoprotein (AFP) in hepatocellular carcinoma (HCC): is this 50-year biomarker still up-to-date?

F Muscari, C Maulat - Translational Gastroenterology and …, 2020 - ncbi.nlm.nih.gov
UICC staging) and tumor size. Although this study is retrospective, it is of interest both by the
issue raised which is still contradictory and by the large size of the cohort studied by the …

Prognostic Value of Serum α‐Fetoprotein Level as an Important Characteristic of Tumor Biology for Patients Undergoing Liver Resection of Early-Stage Hepatocellular …

LQ Yao, ZQ Fan, MD Wang, YK Diao, TH Chen… - Annals of Surgical …, 2024 - Springer
Abstract Background and Objective According to the Barcelona Clinic Liver Cancer (BCLC)
algorithm, tumor burden and liver function, but not tumor biology, are the key factors in …

Synergistic impact of alpha-fetoprotein and tumor burden on long-term outcomes following curative-intent resection of hepatocellular carcinoma

DI Tsilimigras, JM Hyer, A Diaz, F Bagante, F Ratti… - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) tumor burden score (TBS) and α-
fetoprotein (AFP) have been considered important predictors of outcomes among patients …

Does the preoperative alpha‐fetoprotein predict the recurrence and mortality after hepatectomy for hepatocellular carcinoma without macrovascular invasion in …

A Kudo, S Matsumura, D Ban, T Irie… - Hepatology …, 2014 - Wiley Online Library
Aim It has been highly controversial whether elevated serum α‐fetoprotein (AFP) level
before hepatectomy predicts recurrence and mortality of patients with hepatocellular …

Clinical significance of alpha-fetoprotein in alpha-fetoprotein negative hepatocellular carcinoma underwent curative resection

K Lin, Q Huang, J Zeng, Z Ding, L Wang… - Digestive Diseases and …, 2021 - Springer
Background The clinical value of alpha-fetoprotein (AFP) in patients with AFP-negative (< 20
ng/ml) hepatocellular carcinoma (HCC) who underwent curative resection remained …

Postoperative α-fetoprotein response predicts tumor recurrence and survival after hepatectomy for hepatocellular carcinoma: a propensity score matching analysis

XL Li, XD Zhu, H Cai, Y Li, J Zhou, J Fan, ZY Tang… - Surgery, 2019 - Elsevier
Background To investigate the prognostic values of the change of α-fetoprotein within 1
week after resection of hepatocellular carcinoma. Methods We retrospectively analyzed …

Alpha fetoprotein changes predict hepatocellular carcinoma survival beyond the Milan criteria after hepatectomy

J Shen, C Li, T Wen, L Yan, B Li, W Wang… - Journal of Surgical …, 2017 - Elsevier
Background Assessing the outcomes of surgeries for hepatocellular carcinoma (HCC)
patients who exceed the Milan criteria is necessary. Some studies have demonstrated that …