Purpose Cisplatin is a critical component of first‐line chemotherapy for several cancers, but
causes peripheral sensory neuropathy, hearing loss, and tinnitus. We aimed to identify …

Purpose: Cisplatin is a first-line chemotherapeutic for many cancers, but causes
neurotoxicity including hearing loss, tinnitus, and peripheral sensory neuropathy. However …

Purpose: Cisplatin, a commonly used chemotherapeutic, results in tinnitus, the phantom
perception of sound. Our purpose was to identify the clinical and genetic determinants of …

Purpose: Adverse drug reactions such as ototoxicity, which occurs in approximately one-fifth
of adult patients who receive cisplatin treatment, can incur large socioeconomic burdens on …

PURPOSE Cisplatin is widely used and highly ototoxic, but patient-reported functional
impairment because of cisplatin-related hearing loss (HL) and tinnitus has not been …

Purpose: Cisplatin is one of the most commonly used chemotherapy drugs worldwide and
one of the most ototoxic. We sought to identify genetic variants that modulate cisplatin …

Importance Cisplatin-induced ototoxic effects are an important complication that affects
testicular cancer survivors as a consequence of treatment. The identification of genetic …

Purpose Ototoxicity is a prominent side effect of cisplatin-based chemotherapy. There are
few reports, however, estimating its prevalence in well-defined cohorts and associated risk …

In view of advances in early detection and treatment, the 5-year relative survival rate for all
cancer patients combined is now approximately 66%. As a result, there are more than 13.7 …

Ototoxicity is one of the major side-effects of platinum-based chemotherapy, in particular
cisplatin (cis-diammine dichloroplatinum II). To our knowledge, no systematic review has …