Tetherin/BST-2 is a host-encoded protein that restricts a wide diversity of viruses at the stage
of virion release. However, viruses have evolved antagonists of Tetherin, including the Vpu …

Vpu proteins of pandemic HIV-1 M strains degrade the viral receptor CD4 and antagonize
human tetherin to promote viral release and replication. We show that Vpus from SIVgsn …

Tetherin, also known as BST2, CD317 or HM1. 24, was recently identified as an interferon-
inducible host–cell factor that interferes with the detachment of virus particles from infected …

Background The anti-viral activity of the cellular restriction factor, BST-2/tetherin, was first
observed as an ability to block the release of Vpu-minus HIV-1 from the surface of infected …

Summary The tetherin/BST2/CD317 protein blocks the release of HIV-1 and other
enveloped viruses by inducing tethering of nascent particles to infected cell surfaces. The …

Background HIV-1 viruses are categorized into four distinct groups: M, N, O and P. Despite
the same genomic organization, only the group M viruses are responsible for the world-wide …

Tetherin, also known as BST-2/CD317/HM1. 24, is an antiviral cellular protein that inhibits
the release of HIV-1 particles from infected cells. HIV-1 viral protein U (Vpu) is a specific …

The interferon-induced host restriction factor tetherin poses a barrier for SIV transmission
from primates to humans. After cross-species transmission, the chimpanzee precursor of …

Tetherin/BST-2/CD317 is a recently identified antiviral protein that blocks the release of
nascent retrovirus, and other virus, particles from infected cells. An HIV-1 accessory protein …

HIV-1 groups M and N emerged within the last century following two independent cross-
species transmissions of SIVcpz from chimpanzees to humans. In contrast to pandemic …