Background Cannabis is the most frequently used illicit drug worldwide. Although multiple
structural MRI studies of individuals with cannabis use (CB) have been undertaken, the …

Background: Structural imaging studies of cannabis users have found evidence of both
cortical and subcortical volume reductions, especially in cannabinoid receptor-rich regions …

Cannabis exerts its psychoactive effect through cannabinoid receptors that are widely
distributed across the cortical surface of the human brain. It is suggested that cannabis use …

Marijuana is the most commonly used illicit drug in the United States, but little is known
about its effects on the human brain, particularly on reward/aversion regions implicated in …

Rationale Cannabis use is associated with neuroanatomical alterations in the hippocampus.
While the hippocampus is composed of multiple subregions, their differential vulnerability to …

Recent structural MRI studies on gray matter (GM) volumes using group-level mass-
univariate statistical analysis suggest that chronic and heavy cannabis exposure may affect …

Cocaine use disorder (CUD) is a global health problem with serious consequences for both
individuals and society. Previous studies on abnormal anatomical patterns in CUD have …

In animal studies, tetrahydrocannabinol (THC) has been found to affect brain morphology,
particularly within areas rich in cannabinoid receptors (eg, hippocampus, cerebral cortex) …

Background Previous voxel-based morphometric (VBM) and functional magnetic resonance
imaging (fMRI) studies have shown changes in brain structure and function in cocaine …

Regular cannabis use is associated with adverse mental health and neurocognitive
outcomes [1]. To date, there is limited and inconclusive evidence on whether regular …