Disruption of the Aspergillus fumigatus RNA interference machinery alters the conidial transcriptome

AA Kelani, A Bruch, F Rivieccio, C Visser, T Krüger… - RNA, 2023 - rnajournal.cshlp.org
The RNA interference (RNAi) pathway has evolved numerous functionalities in eukaryotes,
with many on display in Kingdom Fungi. RNAi can regulate gene expression, facilitate drug …

RNA interference: roles in fungal biology

H Nakayashiki, QB Nguyen - Current opinion in microbiology, 2008 - Elsevier
The discovery of RNA interference (RNAi) has been the major recent breakthrough in
biology. Only a few years after its discovery, RNAi has rapidly become a powerful reverse …

The RNAi universe in fungi: a varied landscape of small RNAs and biological functions

S Torres-Martínez… - Annual Review of …, 2017 - annualreviews.org
RNA interference (RNAi) is a conserved eukaryotic mechanism that uses small RNA
molecules to suppress gene expression through sequence-specific messenger RNA …

RNA silencing in filamentous fungi: from basics to applications

NB Quoc, H Nakayashiki - … Transformation Systems in Fungi, Volume 2, 2015 - Springer
In the post-genomics era, RNAi has rapidly become a powerful reverse genetic tool for
elucidating gene function in a wide range of eukaryotes including fungi. In this review, we …

RNA interference pathways in fungi: mechanisms and functions

SS Chang, Z Zhang, Y Liu - Annual review of microbiology, 2012 - annualreviews.org
RNA interference (RNAi) is a conserved eukaryotic gene regulatory mechanism that uses
small noncoding RNAs to mediate posttranscriptional/transcriptional gene silencing. The …

RNAi technology: A Novel approaches against fungal infections

M Moazeni, M Nabili, H Badali… - Research in Molecular …, 2014 - rmm.mazums.ac.ir
Despite the introduction of new antifungal agents, resistances to antifungal therapy continue
to increase and outcome of invasive fungal infections treatment is frequently suboptimal. A …

Identification of an active RNAi pathway in Candida albicans

E Iracane, C Arias-Sardá, C Maufrais… - Proceedings of the …, 2024 - National Acad Sciences
RNA interference (RNAi) is a fundamental regulatory pathway with a wide range of
functions, including regulation of gene expression and maintenance of genome stability …

Development-dependent scavenging of nucleic acids in the filamentous fungus Aspergillus fumigatus

C Jöchl, E Loh, A Ploner, H Haas, A Hüttenhofer - RNA biology, 2009 - Taylor & Francis
Aspergillus fumigatus is an ubiquitous, filamentous and opportunistic pathogenic fungus
which causes fatal invasive aspergillosis among immuno-compromised patients. Since …

Different components of the RNA interference machinery are required for conidiation, ascosporogenesis, virulence, deoxynivalenol production, and fungal inhibition …

FY Gaffar, J Imani, P Karlovsky, A Koch… - Frontiers in …, 2019 - frontiersin.org
In filamentous fungi, gene silencing through RNA interference (RNAi) shapes many
biological processes, including pathogenicity. We explored the requirement of key …

RNA interference in fungi: pathways, functions, and applications

Y Dang, Q Yang, Z Xue, Y Liu - Eukaryotic cell, 2011 - Am Soc Microbiol
Small RNA molecules of about 20 to 30 nucleotides function in gene regulation and
genomic defense via conserved eukaryotic RNA interference (RNAi)-related pathways. The …