Somatic evolution and global expansion of an ancient transmissible cancer lineage
A Baez-Ortega, K Gori, A Strakova, JL Allen, KM Allum… - Science, 2019 - science.org
INTRODUCTION The canine transmissible venereal tumor (CTVT) is a sexually transmitted
cancer that manifests as genital tumors in dogs. This cancer first arose in an individual …
cancer that manifests as genital tumors in dogs. This cancer first arose in an individual …
Transmissible dog cancer genome reveals the origin and history of an ancient cell lineage
Canine transmissible venereal tumor (CTVT) is the oldest known somatic cell lineage. It is a
transmissible cancer that propagates naturally in dogs. We sequenced the genomes of two …
transmissible cancer that propagates naturally in dogs. We sequenced the genomes of two …
Comparison against 186 canid whole-genome sequences reveals survival strategies of an ancient clonally transmissible canine tumor
Canine transmissible venereal tumor (CTVT) is a parasitic cancer clone that has propagated
for thousands of years via sexual transfer of malignant cells. Little is understood about the …
for thousands of years via sexual transfer of malignant cells. Little is understood about the …
The cancer which survived: insights from the genome of an 11 000 year-old cancer
A Strakova, EP Murchison - Current opinion in genetics & development, 2015 - Elsevier
The canine transmissible venereal tumour (CTVT) is a transmissible cancer that is spread
between dogs by the allogeneic transfer of living cancer cells during coitus. CTVT affects …
between dogs by the allogeneic transfer of living cancer cells during coitus. CTVT affects …
[HTML][HTML] Clonal origin and evolution of a transmissible cancer
C Murgia, JK Pritchard, SY Kim, A Fassati, RA Weiss - Cell, 2006 - cell.com
The transmissible agent causing canine transmissible venereal tumor (CTVT) is thought to
be the tumor cell itself. To test this hypothesis, we analyzed genetic markers including major …
be the tumor cell itself. To test this hypothesis, we analyzed genetic markers including major …
Extensive conservation of genomic imbalances in canine transmissible venereal tumors (CTVT) detected by microarray-based CGH analysis
R Thomas, C Rebbeck, AM Leroi, A Burt… - Chromosome research, 2009 - Springer
Canine transmissible venereal tumor (CTVT) is an intriguing cancer that is transmitted
naturally as an allograft by transplantation of viable tumor cells from affected to susceptible …
naturally as an allograft by transplantation of viable tumor cells from affected to susceptible …
The changing global distribution and prevalence of canine transmissible venereal tumour
A Strakova, EP Murchison - BMC veterinary research, 2014 - Springer
Background The canine transmissible venereal tumour (CTVT) is a contagious cancer that is
naturally transmitted between dogs by the allogeneic transfer of living cancer cells during …
naturally transmitted between dogs by the allogeneic transfer of living cancer cells during …
[HTML][HTML] The singular history of a canine transmissible tumor
EA Ostrander - Cell, 2006 - cell.com
In this issue of Cell, Murgia et al.(2006) confirm that the infectious agent of canine
transmissible venereal tumor is the cancer cell itself and that the tumor is clonal in origin …
transmissible venereal tumor is the cancer cell itself and that the tumor is clonal in origin …
RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues
INTRODUCTION Cancer genome studies have contributed to the analysis and discovery of
somatic mutations that drive cancer growth. However, studying the genetic makeup of a …
somatic mutations that drive cancer growth. However, studying the genetic makeup of a …
Evaluation of a genetic assay for canine transmissible venereal tumour diagnosis in Brazil
KF Castro, A Strakova, M Tinucci‐Costa… - Veterinary and …, 2017 - Wiley Online Library
The canine transmissible venereal tumour (CTVT) is a transmissible cancer that is spread
between dogs by the allogeneic transfer of living cancer cells. The infectious agents in CTVT …
between dogs by the allogeneic transfer of living cancer cells. The infectious agents in CTVT …