Efficacy of combination of Ezetimibe 10 mg and rosuvastatin 2.5 mg versus rosuvastatin 5 mg monotherapy for hypercholesterolemia in patients with type 2 diabetes

K Torimoto, Y Okada, H Mori, M Hajime… - Lipids in Health and …, 2013 - Springer
Background Statins are used to treat hypercholesterolemia in patients with type 2 diabetes
mellitus, but many of these patients fail to achieve the target LDL-C level. Recent reports …

Effects of combined ezetimibe and simvastatin therapy as compared with simvastatin alone in patients with type 2 diabetes: a prospective randomized double-blind …

P Ruggenenti, D Cattaneo, S Rota, I Iliev… - Diabetes …, 2010 - Am Diabetes Assoc
OBJECTIVE To assess the effects of inhibited gastrointestinal cholesterol absorption in statin-
treated dyslipidemic patients. RESEARCH DESIGN AND METHODS In a multicenter …

Efficacy and safety of ezetimibe and rosuvastatin combination therapy versus those of rosuvastatin monotherapy in patients with primary hypercholesterolemia

W Kim, YE Yoon, SH Shin, JW Bae, BK Hong… - Clinical Therapeutics, 2018 - Elsevier
Purpose The aim of this study was to evaluate the safety and efficacy of combination
treatment of rosuvastatin with ezetimibe in patients with primary hypercholesterolemia …

Effect of fixed‐dose combinations of ezetimibe plus rosuvastatin in patients with primary hypercholesterolemia: MRS‐ROZE (Multicenter Randomized Study of …

KJ Kim, SH Kim, YW Yoon, SW Rha… - Cardiovascular …, 2016 - Wiley Online Library
Aim We aimed to compare the effects of fixed‐dose combinations of ezetimibe plus
rosuvastatin to rosuvastatin alone in patients with primary hypercholesterolemia, including a …

Effect of ezetimibe on LDL-C lowering and atherogenic lipoprotein profiles in type 2 diabetic patients poorly controlled by statins

K Sakamoto, M Kawamura, T Kohro, M Omura… - PLoS …, 2015 - journals.plos.org
Background There exists a subpopulation of T2DM in whom first-line doses of statin are
insufficient for optimally reducing LDL-C, representing a major risk of CVD. The RESEARCH …

Safety and efficacy of ezetimibe added on to rosuvastatin 5 or 10 mg versus up-titration of rosuvastatin in patients with hypercholesterolemia (the ACTE Study)

HE Bays, MH Davidson, R Massaad, D Flaim… - The American journal of …, 2011 - Elsevier
The present multicenter, 6-week, randomized, double-blind, parallel-group, clinical trial
evaluated the safety and efficacy of ezetimibe (10 mg) added to stable rosuvastatin therapy …

Effects of simvastatin and ezetimibe in lowering low-density lipoprotein cholesterol in subjects with type 1 and type 2 diabetes mellitus

K Ciriacks, G Coly, S Krishnaswami… - Metabolic Syndrome …, 2015 - liebertpub.com
Objective: Statins are used to lower total cholesterol (TC) and low-density lipoprotein
cholesterol (LDL-C) levels among patients with type 1 (T1DM) and type 2 diabetes mellitus …

Comparison of the efficacy and safety of rosuvastatin/ezetimibe combination therapy and rosuvastatin monotherapy on lipoprotein in patients with type 2 diabetes …

J Lee, YC Hwang, WJ Lee, JC Won, KH Song… - Diabetes Therapy, 2020 - Springer
Introduction Ezetimibe/statin combination therapy has been reported to provide additional
cardioprotective effects compared to statin monotherapy. The apolipoprotein B/A1 (apoB/A1) …

[HTML][HTML] Comparison of the efficacy of rosuvastatin monotherapy 20 mg with rosuvastatin 5 mg and ezetimibe 10 mg combination therapy on lipid parameters in …

YC Hwang, JE Jun, IK Jeong, KJ Ahn… - … & metabolism journal, 2019 - synapse.koreamed.org
Background The apolipoprotein B/A1 (apoB/A1) ratio is a stronger predictor of future
cardiovascular disease than is the level of conventional lipids. Statin and ezetimibe …

The efficacy and safety of ezetimibe/simvastatin combination compared with intensified lipid‐lowering treatment strategies in diabetic subjects with and without …

JG Jimenez, JB Rosen, V Pirags… - Diabetes, Obesity …, 2013 - Wiley Online Library
Aims The objective was to assess the consistency of effect of switching to
ezetimibe/simvastatin 10/20 mg versus doubling the baseline statin dose (to simvastatin 40 …