Heroin addiction is a disorder that stems from maladaptive plasticity within neural circuits
and produces broad cognitive deficits. Despite considerable advances in psychotherapy …

Drug addiction continues to be an important public health problem, with an estimated 22.6
million current illicit drug users in the United States alone. For many addictions, including …

Background No medications have been proven to be effective for cocaine and
methamphetamine addiction. Attenuation of drug reward has been the main strategy for …

Attenuation of drug reward has been the major focus of medication development in the
addiction area to date. With the growth of research in the area of cognitive neuroscience, the …

Addiction to psychostimulants like cocaine, methamphetamine, and nicotine poses a
continuing medical and social challenge both in the United States and all over the world …

Addiction, as a brain disorder, can be defined with two distinct but interacting components:
drug dependency and neurocognitive deficits. Most of the therapeutic interventions in …

Chronic use of amphetamines and/or opiates has been associated with a wide range of
cognitive deficits, involving domains of attention, inhibitory control, planning, decision …

The incidence of chronic heroin use disorder, including overdose deaths, has reached
epidemic proportions. Here we summarise and evaluate our knowledge of the relationship …

Given the success of cue exposure (extinction) therapy combined with a cognitive enhancer
for reducing anxiety, it is anticipated that this approach will prove more efficacious than …

Objective: Abstinence-based therapy (ABT) and methadone maintenance therapy (MMT) are
common methods of treatment in heroin dependence as both suppress subjective feeling of …