Single-cell transcriptome analysis reveals inter-tumor heterogeneity in bilateral papillary thyroid carcinoma

T Wang, J Shi, L Li, X Zhou, H Zhang, X Zhang… - Frontiers in …, 2022 - frontiersin.org
Background The tumor microenvironment (TME) plays a pivotal role in cancer progression in
papillary thyroid carcinoma (PTC), yet the composition and the phenotype of cells within the …

Single‐cell transcriptomic landscape reveals the differences in cell differentiation and immune microenvironment of papillary thyroid carcinoma between genders

M Peng, G Wei, Y Zhang, H Li, Y Lai, Y Guo, Y Chen… - Cell & bioscience, 2021 - Springer
Background Papillary thyroid carcinoma (PTC) is the main pathological type of thyroid
carcinoma (TC). Gender is a prominent background parameter for patients with PTC. Here …

[HTML][HTML] Papillary thyroid carcinoma landscape and its immunological link with hashimoto thyroiditis at single-cell resolution

J Pan, F Ye, C Yu, Q Zhu, J Li, Y Zhang… - Frontiers in Cell and …, 2021 - frontiersin.org
The tumor microenvironment heterogeneity of papillary thyroid cancer (PTC) is poorly
characterized. The relationship between PTC and Hashimoto thyroiditis (HT) is also in …

Single-cell transcriptomic analysis of ecosystems in papillary thyroid carcinoma progression

T Yan, W Qiu, H Weng, Y Fan, G Zhou… - Frontiers in …, 2021 - frontiersin.org
Background Despite extensive research, the papillary thyroid carcinoma (PTC) ecosystem is
poorly characterized and, in particular, locoregional progression. Available evidence …

Immune cell confrontation in the papillary thyroid carcinoma microenvironment

Z Xie, X Li, Y He, S Wu, S Wang, J Sun, Y He… - Frontiers in …, 2020 - frontiersin.org
Background Papillary thyroid cancer has been associated with chronic inflammation. A
systematic understanding of immune cell infiltration in PTC is essential for subsequent …

Single-cell RNA sequencing revealed a 3-gene panel predicted the diagnosis and prognosis of thyroid papillary carcinoma and associated with tumor immune …

Z Chen, Y Wang, D Li, Y Le, Y Han, L Jia, C Yan… - Frontiers in …, 2022 - frontiersin.org
Objective: Screening prognostic related genes of thyroid papillary carcinoma (PTC) by
single-cell RNA sequencing (scRNA-seq). To construct the diagnostic and prognostic …

Prognostic subtypes of thyroid cancer was constructed based on single cell and bulk-RNA sequencing data and verified its authenticity

F Yang, Y Yu, H Zhou, Y Zhou - Functional & Integrative Genomics, 2023 - Springer
There has been an increase in the mortality rate of thyroid cancer (THCA), which is the most
common endocrine malignancy. We identified six distinct cell types in the THAC …

[HTML][HTML] Transcriptomic analysis of papillary thyroid cancer: a focus on immune-subtyping, oncogenic fusion, and recurrence

SJ Park, YE Kang, JH Kim, JL Park, SK Kim… - Clinical and …, 2022 - ncbi.nlm.nih.gov
Objectives Thyroid cancer is the most common endocrine tumor, with rapidly increasing
incidence worldwide. However, its transcriptomic characteristics associated with …

Multi-omics profiling of papillary thyroid microcarcinoma reveals different somatic mutations and a unique transcriptomic signature

Q Li, T Feng, T Zhu, W Zhang, Y Qian, H Zhang… - Journal of Translational …, 2023 - Springer
Background Papillary thyroid microcarcinoma (PTMC) incidence has significantly increased,
and some cases still exhibit invasive traits. The entire molecular landscape of PTMC, which …

Immune landscape of papillary thyroid cancer and immunotherapeutic implications

KJ Na, H Choi - Endocrine-related cancer, 2018 - erc.bioscientifica.com
Although papillary thyroid cancer (PTC) is curable with excellent survival rate, patients with
dedifferentiated PTC suffer the recurrence or death. As cancer immune escape plays a …