Over the last 50 years, studies investigating the pathogenesis of left ventricular dysfunction
have resulted in many potential therapeutic targets being identified and novel classes of …

While mortality from overt ischaemic heart disease is falling, that from heart failure is
increasing and reaching epidemic proportions. 1 Although an aging population is partly …

Heart failure secondary to myocardial infarction (MI) remains a major source of morbidity
and mortality. Long-term outcome after MI can be largely be defined in terms of its impact on …

In the past decades, myocardial infarction periacute mortality markedly declined since
coronary reperfusion therapy has been adopted. Despite immediate benefits of coronary …

This review briefly highlights the major mechanisms of left ventricular (LV) remodeling
following myocardial infarction in heart failure and presents novel strategies to limit infarct …

Myocardial infarction (MI) is the leading cause of death and morbidity worldwide, with an
incidence relatively high in developed countries and rapidly growing in developing …

Left ventricular (LV) remodeling, which can result from myocardial damage or ventricular
pressure or volume overload, has genomic, cellular, and interstitial components with …

Myocardial infarction (MI) is a leading cause of heart failure. MI is associated with a 7-to 10-
fold greater risk of developing heart failure compared with a normal population. Left …

An understanding of the process of left ventricular (LV) remodeling has led to greater
knowledge of the pathophysiology of heart failure syndrome. This article examines the …

Objectives This study sought to investigate the impact of post-infarct left ventricular (LV)
remodeling on outcomes in the contemporary era. Background LV remodeling after ST …