Low and high cocaine locomotor responding male Sprague–Dawley rats differ in rapid cocaine-induced regulation of striatal dopamine transporter function
BH Mandt, NR Zahniser - Neuropharmacology, 2010 - Elsevier
Adult outbred Sprague–Dawley rats can be classified as either low or high cocaine
responders (LCRs or HCRs, respectively). Importantly, LCRs and HCRs are distinguished …
responders (LCRs or HCRs, respectively). Importantly, LCRs and HCRs are distinguished …
Individual differences in cocaine-and amphetamine-induced activation of male Sprague–Dawley rats: contribution of the dopamine transporter
SK Briegleb, JM Gulley, BR Hoover… - …, 2004 - nature.com
Previously we found that outbred male Sprague–Dawley rats can be classified as either low
or high cocaine responders (LCRs or HCRs, respectively), based on their open-field …
or high cocaine responders (LCRs or HCRs, respectively), based on their open-field …
Low or high cocaine responding rats differ in striatal extracellular dopamine levels and dopamine transporter number
AM Nelson, GA Larson, NR Zahniser - Journal of Pharmacology and …, 2009 - ASPET
Both humans and animals exhibit marked individual differences in cocaine responsiveness.
By using the median split of cocaine-induced locomotor activity, we have classified outbred …
By using the median split of cocaine-induced locomotor activity, we have classified outbred …
Individual differences in cocaine-induced locomotor activity in rats: behavioral characteristics, cocaine pharmacokinetics, and the dopamine transporter
JM Gulley, BR Hoover, GA Larson… - …, 2003 - nature.com
Abstract Outbred male Sprague–Dawley rats can be classified as either low or high cocaine
responders (LCRs or HCRs, respectively) based on their locomotor response to acute …
responders (LCRs or HCRs, respectively) based on their locomotor response to acute …
Rats classified as low or high cocaine locomotor responders: a unique model involving striatal dopamine transporters that predicts cocaine addiction-like behaviors
DJ Yamamoto, AM Nelson, BH Mandt… - Neuroscience & …, 2013 - Elsevier
Individual differences are a hallmark of drug addiction. Here, we describe a rat model based
on differential initial responsiveness to low dose cocaine. Despite similar brain cocaine …
on differential initial responsiveness to low dose cocaine. Despite similar brain cocaine …
Acute cocaine differentially alters accumbens and striatal dopamine clearance in low and high cocaine locomotor responders: behavioral and electrochemical …
J Sabeti, GA Gerhardt, NR Zahniser - Journal of Pharmacology and …, 2002 - ASPET
Behavioral responses of rodents to cocaine are characterized by marked individual
variability. Here, outbred male Sprague-Dawley rats were profiled based on concomitant …
variability. Here, outbred male Sprague-Dawley rats were profiled based on concomitant …
Individual differences in cocaine-induced locomotor sensitization in low and high cocaine locomotor-responding rats are associated with differential inhibition of …
J Sabeti, GA Gerhardt, NR Zahniser - Journal of Pharmacology and …, 2003 - ASPET
Behavioral sensitization to cocaine reflects neuroadaptive changes that intensify drug
effects. However, repeated cocaine administration does not induce behavioral sensitization …
effects. However, repeated cocaine administration does not induce behavioral sensitization …
Individual differences in initial low-dose cocaine-induced locomotor activity and locomotor sensitization in adult outbred female Sprague–Dawley rats
BH Mandt, RM Allen, NR Zahniser - Pharmacology Biochemistry and …, 2009 - Elsevier
Sex and individual differences are important considerations when studying cocaine
responsiveness. We have previously shown that male Sprague–Dawley (S–D) rats can be …
responsiveness. We have previously shown that male Sprague–Dawley (S–D) rats can be …
Mice expressing markedly reduced striatal dopamine transporters exhibit increased locomotor activity, dopamine uptake turnover rate, and cocaine responsiveness
A Rao, A Sorkin, NR Zahniser - Synapse, 2013 - Wiley Online Library
Variations in the expression levels of the dopamine transporter (DAT) can influence
responsiveness to psychostimulant drugs like cocaine. To better understand this …
responsiveness to psychostimulant drugs like cocaine. To better understand this …
Low and high locomotor responsiveness to cocaine predicts intravenous cocaine conditioned place preference in male Sprague–Dawley rats
RM Allen, CV Everett, AM Nelson, JM Gulley… - Pharmacology …, 2007 - Elsevier
Outbred, male Sprague–Dawley rats can be classified as either low or high cocaine
responders (LCRs or HCRs, respectively) based on cocaine-induced locomotor activity in an …
responders (LCRs or HCRs, respectively) based on cocaine-induced locomotor activity in an …