Macrophage mitochondrial and stress response to ingestion of Cryptococcus neoformans

C Coelho, ACO Souza, LS Derengowski… - The Journal of …, 2015 - journals.aai.org
Human infection with Cryptococcus neoformans, a common fungal pathogen, follows
deposition of yeast spores in the lung alveoli. The subsequent host–pathogen interaction …

Inflammatory monocytes are detrimental to the host immune response during acute infection with Cryptococcus neoformans

LJ Heung, TM Hohl - PLoS pathogens, 2019 - journals.plos.org
Cryptococcus neoformans is a leading cause of invasive fungal infections among
immunocompromised patients. However, the cellular constituents of the innate immune …

Phenotypic Switching in Cryptococcus neoformans Contributes to Virulence by Changing the Immunological Host Response

A Guerrero, BC Fries - Infection and immunity, 2008 - Am Soc Microbiol
Cryptococcus neoformans is an encapsulated opportunistic organism that can undergo
phenotypic switching. In this process, the parent smooth colony (SM) switches to a more …

Innate immune evasion strategies against Cryptococcal meningitis caused by Cryptococcus neoformans

CL Yang, J Wang, LL Zou - Experimental and …, 2017 - spandidos-publications.com
As an infectious fungus that affects the respiratory tract, Cryptococcus neoformans (C.
neoformans) commonly causes asymptomatic pulmonary infection. C. neoformans may …

Illuminating the Cryptococcus neoformans species complex: unveiling intracellular structures with fluorescent-protein-based markers

R Shi, X Lin - Genetics, 2024 - academic.oup.com
Cryptococcus neoformans is a fungal pathogen of the top critical priority recognized by the
World Health Organization. This clinically important fungus also serves as a eukaryotic …

Transcriptomic response of Cryptococcus neoformans to ecologically relevant nitrogen concentrations

C Bosch, Z Bhana, B Toplis, H Volschenk… - FEMS Yeast …, 2021 - academic.oup.com
Nitrogen availability is vital for the growth and survival of Cryptococcus neoformans in the
natural environment. Two major ecological reservoirs were previously described for C …

Mechanisms of cryptococcal virulence and persistence

MA Olszewski, Y Zhang, GB Huffnagle - Future microbiology, 2010 - Taylor & Francis
Cryptococcus neoformans is an environmental yeast that is a leading cause of fatal mycosis
in AIDS patients and a major cause of meningoencephalitis and CNS-related mortality …

The transcriptional response of Cryptococcus neoformans to ingestion by Acanthamoeba castellanii and macrophages provides insights into the evolutionary …

LS Derengowski, HC Paes, P Albuquerque… - Eukaryotic …, 2013 - Am Soc Microbiol
Virulence of Cryptococcus neoformans for mammals, and in particular its intracellular style,
was proposed to emerge from evolutionary pressures on its natural environment by …

Real-time imaging of interactions of neutrophils with Cryptococcus neoformans demonstrates a crucial role of complement C5a-C5aR signaling

D Sun, M Zhang, G Liu, H Wu, X Zhu… - Infection and …, 2016 - Am Soc Microbiol
Neutrophils have been shown to efficiently kill Cryptococcus neoformans, a causative agent
of meningoencephalitis. Here, using live-cell imaging, we characterize the dynamic …

The Role of Testosterone and Gibberellic Acid in the Melanization of Cryptococcus neoformans

JS Tucker, TE Guess, EE McClelland - Frontiers in Microbiology, 2020 - frontiersin.org
Cryptococcus neoformans, a spore-producing pathogenic yeast, affects
immunocompromised individuals causing meningoencephalitis. Once C. neoformans is …