Xanthine oxidoreductase (XOR) consists of two different forms, xanthine dehydrogenase
and xanthine oxidase (XO), and is a rate-limiting enzyme of uric acid production from …

Xanthine oxidoreductase (XOR) could contribute to the pathogenesis of metabolic syndrome
through the oxidative stress and the inflammatory response induced by XOR-derived …

Uric acid is the end product of purine metabolism in humans. Hyperuricemia is a metabolic
disease caused by the increased formation or reduced excretion of serum uric acid (SUA) …

Human xanthine oxidoreductase (XOR) is a multiple-level regulated enzyme, resulting from
a complicated evolutionary process that assigned it many physiological roles. The main …

Cardiovascular diseases (CVD) are the leading cause of global mortality and their
pathogenesis lies mainly in the atherosclerotic process. There are close connections linking …

Uric acid is the final oxidation product of purine metabolism in humans. Xanthine
oxidoreductase (XOR) catalyzes oxidative hydroxylation of hypoxanthine to xanthine to uric …

The enzyme xanthine oxidoreductase (XOR) catalyses the last step of purine degradation in
the highest uricotelic primates as a rate-limiting enzyme in nucleic acid catabolism. Although …

There is substantial evidence that oxidative stress participates in the pathophysiology of
cardiovascular disease. Biochemical, molecular and pharmacological studies further …

Background: Xanthine oxidoreductase (XOR) is an enzyme that catalyzes the formation of
uric acid from hypoxanthine and xanthine, leading to an increase in superoxide and reactive …

Obesity and related pathologies such as diabetes and metabolic syndrome are associated
with chronic inflammation and cancer. The serum level of xanthine oxidoreductase (XOR) is …