The major ascending neuromodulator dopamine has long been implicated in cognitive
control. Effects of dopamine-related disorders and the treatment of the cognitive control …

Cognitive control helps us attain our goals by resisting distraction and temptations.
Dopaminergic drugs are well known to enhance cognitive control. However, there is great …

Highlights•Dynamic cognitive control involves cost–benefit decision making.•Cognitive
enhancing drugs alter cognitive control, in part, by increasing dopamine.•Dopamine's effects …

Brain dopamine has often been implicated in impulsive and/or inflexible behaviors, which
may reflect failures of motivational and/or cognitive control. However, the precise role of …

Individual differences in dopaminergic tone underlie tendencies to learn from reward versus
punishment. These effects are well documented in Parkinson's patients, who vacillate …

Evidence from psychopharmacological functional neuroimaging begins to elucidate the
neurochemical mechanisms of cognitive control. Here the role of dopamine in two …

Cognitive control, the ability to orchestrate behavior in accord with our goals, depends on
the prefrontal cortex. These cognitive functions are heavily influenced by the …

Striatal dopamine is an important modulator of current behavior, as seen in the rapid and
dramatic effects of dopamine replacement therapy in Parkinson disease (PD). Yet there is …

Dual system theories suggest that behavioral control is parsed between a deliberative
“model-based” and a more reflexive “model-free” system. A balance of control exerted by …

Our daily decisions are governed by the arbitration between goal-directed and habitual
strategies. However, the neurochemical basis of this arbitration is unclear. We assessed the …