A major research goal in evolutionary genetics is to uncover loci experiencing positive
selection. One approach involves finding 'selective sweeps' patterns, which can either be …

A selective sweep occurs when positive selection drives an initially rare allele to high
population frequency. In nature, the precise parameters of a sweep are seldom known: How …

Characterizing the nature of the adaptive process at the genetic level is a central goal for
population genetics. In particular, we know little about the sources of adaptive substitution or …

For almost 20 years, many inference methods have been developed to detect selective
sweeps and localize the targets of directional selection in the genome. These methods are …

Inferring selective sweeps from genetic data has been a breakthrough in population
genetics. The most prominent examples come from populations suddenly exposed to …

It is increasingly evident that natural selection plays a prominent role in shaping patterns of
diversity across the genome. The most commonly studied modes of natural selection are …

The rate at which beneficial alleles fix in a population depends on the probability of and time
to fixation of such alleles. Both of these quantities can be significantly impacted by …

A strong reduction in diversity around a specific locus is often interpreted as a recent rapid
fixation of a positively selected allele, a phenomenon called a selective sweep. Rapid …

Selective sweeps are typically associated with a local reduction of genetic diversity around
the adaptive site. However, selective sweeps can also quickly carry neutral mutations to …

Positive selection distorts the structure of genealogies and hence alters patterns of genetic
variation within a population. Most analyses of these distortions focus on the signatures of …