Endothelins are powerful vasoconstrictor peptides that also play numerous other functions in
many different organs. Endothelin-1 (ET-1) is the most abundant and important of this family …

The endothelins (ET) are potent 21-amino-acid vasoconstrictor peptides produced in many
different tissues, particularly in the endothelium of blood vessels. ET-1 is the main …

Abstract Endothelin-1 (ET-1) was first characterized as a potent vasoconstrictor and is
overexpressed in the vasculature in different models of hypertension, such as …

Abstract Endothelin-1 (ET-1) is a powerful vasoconstrictor peptide and regulator of blood
flow that plays an important role in blood pressure (BP) elevation in some models of …

The endothelins are a family of endothelium-derived peptides that possess characteristically
sustained vasoconstrictor properties. Endothelin-1 appears to be the predominant member …

Endothelins are a family of peptides, which comprises endothelin-1 (ET-1), endothelin-2 (ET-
2) and endothelin-3 (ET-3), each containing 21 amino-acids. ET-1 is a peptide secreted …

Endothelin-1 (ET-1) is overexpressed in the vascular wall in certain models of experimental
hypertension: deoxycorticosterone acetate salt–treated rats, deoxycorticosterone acetate …

The endothelins are a family of 21–amino acid peptides that are powerful vasoconstrictors.
They may also induce vascular hypertrophy. These peptides may participate through these …

Endothelins are ubiquitously produced 21-amino-acid peptides that were discovered as an
endothelial product and may play important roles in cardiovascular physiology and …

Endothelin-1 is a recently discovered peptide mainly released from endothelial cells.
Hypoxia and ischemia as well as numerous factors such as angiotensin 11, thrombin and …