Fetal growth regulation via insulin-like growth factor axis in normal and diabetic pregnancy

EN Alekseenkova, SA Selkov… - Journal of Perinatal …, 2022 - degruyter.com
Objectives Diabetes mellitus (DM) in pregnancy and gestational diabetes remain a
considerable cause of pregnancy complications, and fetal macrosomia is among them …

Size at birth and insulin-like growth factor-I and its binding protein-1 among infants of diabetic mothers

SA El-Masry, MM El-Ganzoury… - The Journal of …, 2013 - Taylor & Francis
Objective: to estimate the association between intrauterine fetal growth, evaluated by
anthropometric measurements, and biochemical growth factors; IGF-I and IGBP-1 among …

[PDF][PDF] Insulin-like growth factor axis in pregnancy and gestational diabetes mellitus

K Anderlová, A Cinkajzlová, P Šimják… - Physiological …, 2019 - biomed.cas.cz
The insulin-like growth factor (IGF) is involved in the regulation of growth and metabolism.
The aim of this study was to determine selected parameters of IGF system at systemic and …

Maternal insulin‐like growth factors and insulin‐like growth factor‐binding proteins for macrosomia prediction in diabetic and nondiabetic pregnancy: A prospective …

EN Alekseenkova, VN Babakov… - … of Gynecology & …, 2023 - Wiley Online Library
Objective Attributable to the insulin‐like growth factor (IGF) axis involvement in fetal growth
regulation, possible contribution of the maternal IGF axis to antenatal fetal macrosomia …

IGF-1 is associated with fetal growth and preterm delivery in type 1 diabetic pregnancy

FF Lauszus, J Fuglsang - Gynecological Endocrinology, 2016 - Taylor & Francis
Aim: No data on IGF-1 and either preterm or preeclampsia have been reported so far in
diabetic pregnancies. We evaluated consecutive measurements of IGF-1 for preeclampsia …

Inverse changes in fetal insulin‐like growth factor (IGF)‐1 and IGF binding protein‐1 in association with higher birth weight in maternal diabetes

RS Lindsay, JA Westgate, J Beattie… - Clinical …, 2007 - Wiley Online Library
Objective The insulin like growth factor (IGF) system plays a key role in regulating fetal
growth, is metabolically regulated, and may influence development of increased birth weight …

Maternal and fetal IGF-I and IGF-II levels, fetal growth, and gestational diabetes

ZC Luo, AM Nuyt, E Delvin, F Audibert… - The Journal of …, 2012 - academic.oup.com
Context: It remains uncertain whether maternal IGF-I is associated with fetal growth. Little is
known about the role of maternal IGF-II in fetal growth and whether IGF-I or IGF-II is …

Insulin-like growth factors I and II peptide and messenger RNA levels in macrosomic infants of diabetic pregnancies

S Roth, MP Abernathy, WH Lee, L Pratt… - Journal of the …, 1996 - journals.sagepub.com
Objective: Fetal macrosomia is a common complication of maternal diabetes mellitus and is
associated with substantial morbidity, but the precise cellular and molecular mechanisms …

The Influence of Gestational Diabetes Mellitus upon the Selected Parameters of the Maternal and Fetal System of Insulin-Like Growth Factors (IGF-1, IGF-2, IGFBP1-3) …

T Gęca, A Kwaśniewska - Journal of clinical medicine, 2020 - mdpi.com
Background: Gestational diabetes mellitus (GDM), defined as impaired glucose tolerance
with onset or first recognition in pregnancy, increases the risk of not only maternal but also …

Insulin-like growth factors (IGFs) and IGF-binding proteins (IGFBP-1,-2 and-3) in diabetic pregnancy: relationship to macrosomia

YANJUN LIU, T TSUSHIMA, S MINEI, M SANAKA… - Endocrine …, 1996 - jstage.jst.go.jp
To evaluate the role of insulin-like growth factors (IGFs) and IGF-binding proteins (IGFBPs)
in exessive fetal growth (macrosomia) in diabetic pregnancy, 84 insulin-treated diabetic …