In the next few years, blockbuster drugs generating $35 billion in US sales will lose patent
protection or other forms of exclusivity. That means generic drugmakers can quickly launch …

Research into treatments for viral infections has traditionally focused on viral targets. This is
also true for RNA viruses, where common targets include viral RNA-dependent RNA …

Repurposing drugs requires finding novel therapeutic indications compared to the ones for
which they were already approved. This is an increasingly utilized strategy for finding novel …

Sevelamer, an insoluble crosslinked polyallylamine, is a noncalcium phosphate binder used
for the control of hyperphosphatemia in advanced chronic kidney disease, but although it is …

Tolcapone is known as a catechol-O-methyltransferase (COMT) inhibitor, used as an adjunct
in the treatment of Parkinson's disease to protect Dopa drugs against excessive degradation …

Drug repurposing, the idea of finding new uses for authorized drugs, can be cheaper and
faster than developing new compounds. Yet, repurposing remains underutilized, partially …

Generic Drug Challenges Prior to Patent Expiration C. Scott Hemphill* and Bhaven N. Sampat†
December 7, 2009 Draft Preliminary Page 1 Generic Drug Challenges Prior to Patent …