Drug repurposing as a current strategy in medicine discovery

LM Botella - 2022 - digital.csic.es
Drug repurposing (DRP)(also known as drug repositioning) means establishing new
medical uses for already known drugs. Although this is not a new strategy, it has become …

Presenting the bill: a research about the costs and barriers in drug rediscovery

S Berg - 2019 - studenttheses.uu.nl
INTRODUCTION–Drug rediscovery (DR) provides opportunities for new treatments and
patient benefit. However, due to the barriers and the lack of an incentive in the rediscovery …

Regulatory considerations and intellectual property rights of repurposed drugs.

H Afzaal, T Waseem, A Saeed, FA Noori… - Progress in Molecular …, 2024 - europepmc.org
Drug repurposing has emerged as a promising approach in the drug discovery and
development process as it offers safe and effective therapeutic options in a time effective …

Drug Repurposing Patent Applications October–December 2014

HAM Mucke - ASSAY and Drug Development Technologies, 2015 - liebertpub.com
Second-and third-generation nitrogen-containing bisphosphonates are the gold standard for
the treatment of osteoporosis. They have a rare but severe side effect, osteonecrosis of the …

Drug repurposing from an academic perspective

TI Oprea, JE Bauman, CG Bologa, T Buranda… - Drug Discovery Today …, 2011 - Elsevier
Academia and small business research units are poised to play an increasing role in drug
discovery, with drug repurposing as one of the major areas of activity. Here we summarize …

A novel approach for drug discovery-drug repurposing

M Meera, S Sekar, R Mahatao - National Journal of …, 2022 - search.proquest.com
Drug repurposing refers to finding a new indication for a pre-existing drug. It is a novel way
of drug discovery that greatly reduces the time and money spent in the drug discovery …

13 Advantages, opportunities, and challenges to drug repurposing

K Sharma, H Shrivastava, A Kumar - Drug Repurposing, 2023 - degruyter.com
Drug repurposing, also known as drug repositioning or drug reprofiling, involves
establishing new therapeutic indications for a clinically well-established drug. The drug …

Can old drugs learn new tricks? Achieving registration and public subsidy listing for off‐patent medicines with novel therapeutic applications

J Brett, D Bahceci, W Lipworth… - Internal Medicine …, 2023 - Wiley Online Library
With the increasing costs of drug development, repurposing of low‐cost medicines for new
indications has never been more important. However, there are multiple barriers to …

Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers

CG Begley, M Ashton, J Baell, M Bettess… - Science Translational …, 2021 - science.org
Drug repurposing is promoted as a cost-and time-effective mechanism for providing new
medicines. Often, however, there is insufficient consideration by academic researchers of …

Comparing regulatory pathways for drug repurposing in the EU, UK, and US

M Scholte, L Bendicksen… - RExPO22 …, 2023 - drugrepocentral.scienceopen.com
Drug repurposing may be useful in efficiently bringing important new treatments to patients.
To help investigators interested in drug repurposing–particularly those in academic or non …