Fractional flow reserve (FFR) is considered nowadays as the gold standard for invasive
assessment of physiologic stenosis significance and an indispensable tool for decision …

Aims In patients submitted to coronary angiography, fractional flow reserve (FFR)
assessment by a pressure wire can be used to guide the decision for revascularization …

Computations of fractional flow reserve, based on CT coronary angiography and
computational fluid dynamics (CT-based FFR) to assess the severity of coronary artery …

Objectives. The aim of this study was to analyse the rate of major adverse clinical events in
patients with coronary artery disease and a fractional flow reserve (FFR) of≥ 0.75 and …

Although atherosclerotic lesion burden and severity is a continuum, the decision to
revascularize a patient or not is a dichotomous one. Therefore, like other quantitative cutoffs …

Aims: The aim of this study was to validate novel software to calculate vessel fractional flow
reserve (vFFR) based on 3D-QCA and to assess inter-observer variability in patients who …

Evaluation of new coronary devices and demonstration of their conformity to essential
principles of safety and effectiveness requires clinical trials in human subjects. Today, many …

Guidelines recommend using hyperemic (FFR) and non-hyperemic (iFR/RFR) methods of
evaluating coronary artery stenoses in patients with coronary artery disease. However, in …

Background Physiological assessment of intermediate coronary lesions to guide coronary
revascularization is currently recommended by international guidelines. Vessel fractional …

New non-and less-invasive techniques have been developed to overcome the procedural
and operator related burden of the fractional flow reserve (FFR) for the assessment of …