Resveratrol as a modulatory of apoptosis and autophagy in cancer therapy

R Yang, H Dong, S Jia, Z Yang - Clinical and Translational Oncology, 2022 - Springer
Cancer is one of the leading causes of death, with a heavy socio-economical burden for
countries. Despite the great advances that have been made in the treatment of cancer …

Targeting of cancer cell death mechanisms by resveratrol: a review

X Fu, M Li, C Tang, Z Huang, M Najafi - Apoptosis, 2021 - Springer
Cancer cell death is the utmost aim in cancer therapy. Anti-cancer agents can induce
apoptosis, mitotic catastrophe, senescence, or autophagy through the production of free …

Mechanism of resveratrol-induced programmed cell death and new drug discovery against cancer: a review

JY Jang, E Im, ND Kim - International journal of molecular sciences, 2022 - mdpi.com
Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene), a polyphenol found in grapes, red wine,
peanuts, and apples, has been reported to exhibit a wide range of biological and …

Resveratrol as an enhancer of apoptosis in cancer: a mechanistic review

M Ashrafizadeh, S Taeb… - Anti-Cancer Agents …, 2021 - ingentaconnect.com
The resistance to therapy of cancer cells is a challenge for achieving an appropriate
therapeutic outcome. Cancer (stem) cells possess several mechanisms for increasing their …

Resveratrol, a phytochemical inducer of multiple cell death pathways: apoptosis, autophagy and mitotic catastrophe

D Delmas, E Solary, N Latruffe - Current medicinal chemistry, 2011 - ingentaconnect.com
Cancers are the largest cause of mortality and morbidity in industrialized countries. In the
field of the medicinal chemistry of natural products, numerous studies have reported …

Resveratrol induces apoptosis via ROS-triggered autophagy in human colon cancer cells

H Miki, N Uehara, A Kimura… - International …, 2012 - spandidos-publications.com
Abstract Resveratrol (Res; 3, 4', 5-trihydroxy-trans-stilbene), which is a polyphenol found in
grapes, can block cell proliferation and induce growth arrest and/or cell death in several …

Apoptotic cell death induced by resveratrol is partially mediated by the autophagy pathway in human ovarian cancer cells

F Lang, Z Qin, F Li, H Zhang, Z Fang, E Hao - PloS one, 2015 - journals.plos.org
Resveratrol (trans-3, 4, 5'–trihydroxystilbene) is an active compound in food, such as red
grapes, peanuts, and berries. Resveratrol exhibits an anticancer effect on various human …

Resveratrol induces autophagy-dependent apoptosis in HL-60 cells

Y Fan, JF Chiu, J Liu, Y Deng, C Xu, J Zhang, G Li - BMC cancer, 2018 - Springer
Background All known mechanisms of apoptosis induced by resveratrol act through cell
cycle arrest and changes in mitochondrial membrane potential. It is currently unknown …

Resveratrol modulates the apoptosis and autophagic death of human lung adenocarcinoma A549 cells via a p53‑dependent pathway: Integrated bioinformatics …

Y Fan, J Li, Y Yang, X Zhao, Y Liu… - International …, 2020 - spandidos-publications.com
Resveratrol (RSV) has been reported to exhibit cytotoxic activity in multiple types of
malignant cells; however, the mechanisms underlying the antitumor effects of RSV in non …

Resveratrol as a natural regulator of autophagy for prevention and treatment of cancer

Y Tian, W Song, D Li, L Cai, Y Zhao - OncoTargets and therapy, 2019 - Taylor & Francis
Resveratrol, as a natural product compound, has been recently attracted much attention for
its potent effects on cancer. Cancer is a serious disease threatening human survival and …