Background: Sex and gender-based differences are observed well beyond the sex organs
and affect several physiological and biochemical processes involved in the metabolism of …

In humans, the combination of all sex-specific genetic, epigenetic, and hormonal influences
of biologic sex produces different in vivo environments for male and female cells. We dissect …

Physiological, hormonal, and genetic differences between males and females affect the
prevalence, incidence, and severity of diseases and responses to therapy. Understanding …

There are a number of examples of sex differences in drug pharmacokinetics and
pharmacodynamics. Recent advances in the characterisation of specific isozymes involved …

Pharmacological response depends on multiple factors and one of them is sex–gender.
Data on the specific effects of sex–gender on pharmacokinetics, as well as the safety and …

Significant differences that exist between the sexes affect the prevalence, incidence and
severity of a broad range of diseases and conditions. Men and women also differ in their …

Increasing clinical data on sex-related differences in drug efficacy and toxicity has
highlighted the importance of understanding the impact of sex on drug pharmacokinetics …

In this review I have attempted to summarize gender differences in pharmacokinetics
involving the cytochrome P450 (CYP) isozymes of young and mature adults, excluding the …

Gender-related differences in pharmacokinetics have frequently been considered as
potentially important determinants for the clinical effectiveness of drug therapy. The …

The effects of sex on pharmacogenetically guided drug treatment | Pharmacogenomics Future
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