Different effects of normal aging on muscarinic and nicotinic receptor subtypes were
observed in postmortem brain tissue from different regions of the human brain. A significant …

The main objective of the present study was to determine whether cholinergic markers
(choline acetyl‐transferase activity and nicotinic and muscarinic receptors) are altered in …

Cholinergic nicotinic and muscarinic receptor binding were measured in post mortem
human brain tissue, using low (nM) concentrations of (3 H)-nicotine to detect predominately …

Nicotinic and muscarinic cholinergic receptors were studied in autopsied brains from four
histologically normal controls and five histopathologically verified cases of Alzheimer‐type …

Multiple neuroreceptor changes are present in Alzheimer disease. These observations are
based upon analysis from autopsy brain tissue or more seldom from neurosurgical biopsies …

Muscarinic (cholinergic) receptor binding sites (MRB) were studied by determining the 3H-
QNB binding in four cortical areas and hippocampus of 20 histologically confirmed …

Brain nicotinic receptors were studied in the frontal cortex, temporal cortex, hippocampus
and caudate nucleus in patients with Parkinson's disease (PD), Alzheimer's disease (AD) …

The muscarinic receptor subtypes determined by displacing [3 H] quinuclidinyl benzylate by
carbachol showed distinct profiles in Alzheimer's disease (AD) and in Parkinson's disease …

Molecular subtypes of muscarinic receptors (m1–m5) are novel targets for cholinergic
replacement therapies in Alzheimer's disease. However, the status of these receptors in …

Nicotinic cholinergic receptors were measured in human frontal cortex using [3 H] nicotine
and [3 H] acetylcholine (in the presence of atropine) as receptor ligands. A parallel marked …