The lungs are major sites of metastases for several cancer types, including breast cancer
(BC). Prognosis and quality of life of BC patients that develop pulmonary metastases are …

Lung cancers remain the leading cause of cancer-related death in both men and women.
Infiltrating immune cells in the tumor microenvironment (TME) play a critical role in the …

Abstract Treatment options are limited for patients with breast cancer presenting with
metastatic disease. Targeting of tumor-associated macrophages through the inhibition of …

Exosomes are small vesicle cellular products originating from the endocytic pathway
abundantly secreted by tumor cells. These exosomes have the ability to alter their immediate …

Lung metastasis is a common and deadly occurrence in many types of solid tumors.
Chemokine receptor CXCR4 and transcription factor signal transducer and activator of …

Background: Most cancer patients die of metastatic disease, and in a high proportion of
cases, from lung metastasis. Methods to target therapy to metastatic disease in general and …

Metronomic chemotherapy in combination with immunotherapy is an attractive approach in
cancer therapy. The purpose of the present study was to investigate the anti-tumor effect of …

Lung cancer is the most common cause of cancer-related deaths. Lung cancers can be
classified as small-cell (SCLC) or non-small cell (NSCLC). About 84% of all lung cancers …

Lung metastasis is a critical cause of cancer mortality and its therapy is largely challenged
by the limited drug delivery efficiency and robust immunosuppression in metastatic tumors …

The biomimetic delivery system (BDS) based on special types of endogenous cells like
macrophages and T cells, has been emerging as a novel strategy for cancer therapy, due to …