Mitochondria are the principal place of energy metabolism and ROS production, leading to
mtDNA being especially sensitive to the impacts of oxidative stress. Our review aims to …

Unmitigated UV radiation (UVR) induces skin photoaging and multiple forms of cutaneous
carcinoma by complex pathways that include those mediated by UV-induced reactive …

The skin is a high turnover organ, and its constant renewal depends on the rapid
proliferation of its progenitor cells. The energy requirement for these metabolically active …

Ultraviolet B (UVB) radiation is the leading cause of premature skin aging and skin cancer.
UVB mediated mitochondrial dysfunction has been identified as one of the causative factors …

Melatonin (N-acetyl-5-methoxytryptamine) is recognized as an effective antioxidant
produced by the pineal gland, brain and peripheral organs, which also has anti …

Skin ageing is the result of a loss of cellular function, which can be further accelerated by
external factors. Mitochondria have important roles in skin function, and mitochondrial …

Introduction The analysis of the role of the mitochondria in oxidative damage and skin aging
has been a significant aspect of dermatological research. Mitochondria generate most …

The skin is regularly exposed to the harmful effects of sunlight, such as ultraviolet radiation
(UVR), which leads to ageing effects as well as clinical precancerous lesions and skin …

Chronic exposure to Ultraviolet B radiation (UV‐B) evokes a myriad of toxic signalling events
in the irradiated skin. One of such response is ER stress, which is known to exacerbate …

Mitochondria, long considered to have the primary role in cellular energetic, have been the
center of much research interest in the recent past. Technological advances in microscopy …