Host immunity and inflammation to pulmonary helminth infections

JE Weatherhead, P Gazzinelli-Guimaraes… - Frontiers in …, 2020 - frontiersin.org
Helminths, including nematodes, cestodes and trematodes, are complex parasitic organisms
that infect at least one billion people globally living in extreme poverty. Helminthic infections …

Helminth modulation of lung inflammation

C Schwartz, E Hams, PG Fallon - Trends in parasitology, 2018 - cell.com
Parasitic helminths must establish chronic infections to complete their life cycle and
therefore are potent modulators of multiple facets of host physiology. Parasitic helminths …

Helminths in the lungs

JM Craig, AL Scott - Parasite immunology, 2014 - Wiley Online Library
Parasitic helminths infect well over one billion people and typically cause chronic and
recurrent infections that exert a considerable toll on human health and productivity. A …

Regulation of allergy and autoimmunity in helminth infection

MS Wilson, RM Maizels - Clinical reviews in allergy & immunology, 2004 - Springer
Parasitic infections are a major theme in the “hygiene hypothesis”, as allergies and
autoimmune diseases are less prevalent in countries with higher burdens of helminths and …

Using eggs from Schistosoma mansoni as an in vivo model of helminth-induced lung inflammation

KL Joyce, W Morgan, R Greenberg, MG Nair - JoVE (Journal of Visualized …, 2012 - jove.com
Schistosoma parasites are blood flukes that infect an estimated 200 million people
worldwide 1. In chronic infection with Schistosoma, the severe pathology, including liver …

Helminth infections and host immune regulation

HJ McSorley, RM Maizels - Clinical microbiology reviews, 2012 - Am Soc Microbiol
Helminth parasites infect almost one-third of the world's population, primarily in tropical
regions. However, regions where helminth parasites are endemic record much lower …

[HTML][HTML] Regulation of the host immune system by helminth parasites

RM Maizels, HJ McSorley - Journal of Allergy and Clinical Immunology, 2016 - Elsevier
Helminth parasite infections are associated with a battery of immunomodulatory
mechanisms that affect all facets of the host immune response to ensure their persistence …

Intestinal helminth infection promotes IL-5- and CD4+ T cell-dependent immunity in the lung against migrating parasites

KJ Filbey, M Camberis, J Chandler, R Turner… - Mucosal …, 2019 - nature.com
The ability of helminths to manipulate the immune system of their hosts to ensure their own
survival is often credited with affecting responses to other pathogens. We undertook co …

Regulation of pathogenesis and immunity in helminth infections

RM Maizels, EJ Pearce, D Artis… - Journal of Experimental …, 2009 - rupress.org
Helminths are multicellular eukaryotic parasites that infect over one quarter of the world's
population. Through coevolution with the human immune system, these organisms have …

T-cell regulation in helminth parasite infections: implications for inflammatory diseases

R Maizels, M Yazdanbakhsh - T Cell Regulation in Allergy, Asthma and …, 2008 - karger.com
The field of infectious disease immunology is at an exciting intersection with new concepts in
immune regulation meeting with the dynamics of infectious diseases. We discuss how the …