C3 glomerulopathy describes a spectrum of disorders with glomerular pathology associated
with C3 cleavage product deposition and with defective complement action and regulation …

The complement system functions as a part of the innate immune system. Inappropriate
activation of the complement pathways has a deleterious effect on kidneys. Recent …

C3 glomerulopathy is a recently defined entity that encompasses a group of kidney diseases
caused by abnormal control of complement activation with deposition of complement …

Abstract C3 glomerulopathy (C3G) is a rare disease resulting from dysregulation of the
alternative complement pathway, resulting in the deposition of complement component 3 …

Abstract C3 glomerulopathy (C3G) is a rare and complex kidney disease that primarily
affects young adults. Renal outcomes remain poor in the absence of specific treatment. C3G …

Abstract C3 glomerulopathy (C3G) describes a pathologic pattern of injury diagnosed by
renal biopsy. It is characterized by the dominant deposition of the third component of …

C3 Glomerulopathies, which include Dense Deposit Disease and C3 Glomerulonephritis,
are associated with genetic and acquired dysregulation of the C3 convertase alternative …

Abstract C3 glomerulopathy (C3G) describes a spectrum of glomerular diseases defined by
shared renal biopsy pathology: a predominance of C3 deposition on immunofluorescence …

Background C3 glomerulopathy (C3G) defines a group of rare complement-mediated kidney
diseases with a shared underlying pathophysiology: dysregulation of complement in the …

The C3 glomerulopathies are a group of rare kidney diseases characterized by complement
dysregulation occurring in the fluid phase and in the glomerular microenvironment, which …