Glaucoma [1-8] and macular degeneration [9-11] are among the ophthalmologic diseases
increasingly affecting the aging population worldwide. It is estimated that around 76 million …

Fixed combination drugs can provide effective lOP control, enhance adherence and
convenience, eliminate the washout effect, and significantly reduce exposure to …

In the 21st century there are more highly effective medical management options for
glaucoma than there were in the 1980s and 1990s. In deciding among them, the clinician's …

Open-angle glaucoma is a multifactorial optic neuropathy characterized by progressive loss
of retinal ganglion cells and their axons. It is an irreversible disease with no established …

Objectives: To analyse drug development for open-angle glaucoma during the last 20 years.
Methods: Research was performed by referring to clinical trials registered at the International …

The armamentarium for the medical treatment of glaucoma recently experienced an
unprecedented expansion of available agents. Years ago, the choice was limited to miotics …

ABSTRACT Introduction Fixed dose combinations (FCs) represent a potentially valuable
treatment strategy in glaucoma management. Fixed combinations not only improve …

The addition of new glaucoma medications in the past few years, including several with
once daily dosing and improved efficacy, has greatly expanded medical therapy options for …

Glaucoma is defined by a typical optic neuropathy accompanied by characteristic visual field
loss and eventual blindness. The major risk factor for glaucoma is elevated intraocular …