[HTML][HTML] Platelet innate immune receptors and TLRs: a double-edged sword

T Ebermeyer, F Cognasse, P Berthelot… - International journal of …, 2021 - mdpi.com
Platelets are hematopoietic cells whose main function has for a long time been considered
to be the maintenance of vascular integrity. They have an essential role in the hemostatic …

[HTML][HTML] Regulation of innate immune responses by platelets

LS Ribeiro, L Migliari Branco, BS Franklin - Frontiers in immunology, 2019 - frontiersin.org
The role of platelets has been extensively studied in the context of coagulation and vascular
integrity. Their hemostatic imbalance can lead to known conditions as atherosclerotic …

Platelet toll-like receptors are crucial sensors of infectious danger moieties

H Hamzeh-Cognasse, P Berthelot, B Tardy, B Pozzetto… - Platelets, 2018 - Taylor & Francis
In addition to their haemostatic role and function in the repair of damaged vascular
epithelium, platelets play a defensive role in innate immunity, having the capacity to produce …

[HTML][HTML] The inflammatory role of platelets via their TLRs and Siglec receptors

F Cognasse, KA Nguyen, P Damien, A McNicol… - Frontiers in …, 2015 - frontiersin.org
Platelets are non-nucleated cells that play central roles in the processes of hemostasis,
innate immunity, and inflammation; however, several reports show that these distinct …

[HTML][HTML] Revisiting platelets and toll-like receptors (TLRs): at the interface of vascular immunity and thrombosis

K Hally, S Fauteux-Daniel… - International journal of …, 2020 - mdpi.com
While platelet function has traditionally been described in the context of maintaining
vascular integrity, recent evidence suggests that platelets can modulate inflammation in a …

Small but mighty: platelets as central effectors of host defense

TJ Stocker, IA Hellen, M Steffen… - Thrombosis and …, 2017 - thieme-connect.com
Platelets actively participate in inflammatory processes and drive diseases such as
atherosclerosis, rheumatoid arthritis and cancer metastasis. However, platelets also have …

Platelet Toll-like receptor expression: the link between “danger” ligands and inflammation

O Garraud, F Cognasse - Inflammation & Allergy-Drug Targets …, 2010 - ingentaconnect.com
Platelets are non-nucleated cellular elements that play a role in hemostasis, innate
immunity, and inflammation. Platelet-linked inflammation seems essentially related to the …

Platelet toll-like receptors in thromboinflammation

LP D'Atri, MA Schattner - 2017 - ri.conicet.gov.ar
Besides their undiscussed role in hemostasis and thrombosis, platelets are also key effector
cells capable of assisting and modulating inflammatory reactions and immune responses …

Platelets and innate immunity

JW Semple, J Freedman - Cellular and Molecular Life Sciences, 2010 - Springer
Although platelets are best known as primary mediators of hemostasis, this function
intimately associates them with inflammatory processes, and it has been increasingly …

Crosstalk between platelets and the immune system: old systems with new discoveries

C Li, J Li, Y Li, S Lang, I Yougbare, G Zhu… - Advances in …, 2012 - Wiley Online Library
Platelets are small anucleate cells circulating in the blood. It has been recognized for more
than 100 years that platelet adhesion and aggregation at the site of vascular injury are …