Estrogen has a pivotal role in many biological functions in both reproductive and non-
reproductive organs, mediating actions through its receptors, estrogen receptor?(ER?) and …

Estrogen is an important sex steroid hormone which serves an important role in the
regulation of a number of biological functions, including regulating bone density, brain …

In recent years, researchers have demonstrated that estrogen and its receptors, aside from
their role in regulating several biological functions, contribute to the development and …

The regulatory role of estrogens and nuclear estrogen receptors, ie, estrogen receptor α and
β has been reported in gastrointestinal diseases. However, the contribution of G protein …

Upon binding their cognate receptors, ERα (ESR1) and ERβ (ESR2), estrogens activate
intracellular signaling cascades that have important consequences for cellular behavior …

The estrogen-related receptor alpha (ERRα) is a primary regulator of mitochondrial energy
metabolism, function and dynamics, and has been implicated in autophagy and immune …

Hormones have become a useful therapeutic aspect of clinical endocrinology but how to use
them to optimize the health benefits and avoid adverse effects is a major challenge …

Worldwide, gastric cancer is one of the most common malignancies with high mortality.
Various aspects of the development and progression of gastric cancer continue to be …

Epidemiological studies show that oestrogen reduces the risk of colorectal cancer in
postmenopausal women and ERβ (oestrogen receptor β)-selective ligands have been …

The discovery of the second estrogen receptor (ER) in 1995 surprised many
endocrinologists and resulted in some scepticism regarding its physiological importance …