The colonic mucus barrier serves as a primary defense against enteric pathogens;
destruction of this mucus layer has been observed in ulcerative colitis patients. This study …

Puerarin is a kind of isoflavones in Puerariae Lobatae Radix with physiological activities,
such as anti-inflammatory and vasodilatory activities. The aim of this study was to investigate …

The intestinal barrier is essential for maintaining human intestinal health. The growing
number of studies has shown that both puerarin and tryptophan and its metabolites have a …

Abstract Mucin 2 (MUC2) is the skeleton of colonic mucus that comprises the physical
intestinal barrier. Different dietary polysaccharides may affect colonic mucus at different …

Maintaining a steady state of mucus barrier is an important potential target for polyphenol to
exert its anticolitis activity. This study elucidates the pivotal role of polyphenol rosmaric acid …

Phloretin, extracted from the pericarp and velamen of apples or pears, is a dihydrochalcone
flavonoid with anti-bacterial and anti-inflammatory activities. It has been reported that …

Gut dysbiosis and bile acid (BA) metabolism disturbance are involved in the pathogenesis of
ulcerative colitis. This study aimed to investigate the effect of fucoidan on BA metabolism …

Ulcerative colitis (UC) is an inflammatory bowel disease accompanied by abdominal pain,
diarrhea, and rectal bleeding. The aim of this study was to investigate whether puerarin, one …

Ulcerative colitis (UC) is a chronic and relapsing inflammatory bowel disorder in the colon
and rectum leading to low life‐quality and high societal costs. Ursolic acid (UA) is a natural …

Control of inflammation and mucin expression is important in managing inflammatory bowel
disease (IBD). This study investigated the effects of an ethanol extract of Ramulus mori …