Endothelin-1 (ET-1) is overexpressed in the vascular wall in certain models of experimental
hypertension: deoxycorticosterone acetate salt–treated rats, deoxycorticosterone acetate …

Abstract Endothelin-1 (ET-1) is a powerful vasoconstrictor peptide and regulator of blood
flow that plays an important role in blood pressure (BP) elevation in some models of …

Abstract Endothelin-1 (ET-1) was first characterized as a potent vasoconstrictor and is
overexpressed in the vasculature in different models of hypertension, such as …

The endothelins (ET) are potent 21-amino-acid vasoconstrictor peptides produced in many
different tissues, particularly in the endothelium of blood vessels. ET-1 is the main …

Endothelins are powerful vasoconstrictor peptides that also play numerous other functions in
many different organs. Endothelin-1 (ET-1) is the most abundant and important of this family …

Abstract Endothelin-1 (ET-1) is a powerful vasoconstrictor and mitogen that contributes to
blood pressure elevation and related vascular remodeling and target organ damage. ET-1 …

We previously showed that endothelin-1 expression was increased in vascular endothelium
of deoxycorticosterone acetate–salt hypertensive rats, whereas in spontaneously …

To investigate the possible involvement of endothelin-1 (ET-1), an endothelium-derived
potent vasoconstrictor peptide, in the pathophysiology of hypertension, plasma ET-1 levels …

Abstract Endothelin (ET)-1 is a potent vasoconstrictor peptide which is also endowed with
hypertrophic and mitogenic properties. Enhanced ET-1 gene expression in blood vessels of …

The endothelins are a family of 21–amino acid peptides that are powerful vasoconstrictors.
They may also induce vascular hypertrophy. These peptides may participate through these …