Undaria pinnatifida fucoidan nanoparticles loaded with quinacrine attenuate growth and metastasis of pancreatic cancer

SM Etman, RA Mehanna, AA Bary… - International Journal of …, 2021 - Elsevier
Pancreatic cancer is a devastating gastrointestinal tumor with limited Chemotherapeutic
options. Treatment is restricted by its poor vascularity and dense surrounding stroma …

[HTML][HTML] Hesperetin conjugated PEGylated gold nanoparticles exploring the potential role in anti-inflammation and anti-proliferation during diethylnitrosamine-induced …

G Krishnan, J Subramaniyan, PC Subramani… - Asian journal of …, 2017 - Elsevier
Liver cancer is the fifth most common cancer and one of the leading causes of death in the
world, and second most common cause of death in men. Natural products emerge as the …

[HTML][HTML] Formulation and evaluation of kaempferol loaded nanoparticles against experimentally induced hepatocellular carcinoma: in vitro and in vivo studies

I Kazmi, FA Al-Abbasi, M Afzal, HN Altayb, MS Nadeem… - Pharmaceutics, 2021 - mdpi.com
The present study was designed to prepare Kaempferol loaded nanoparticles (KFP-Np) and
evaluate hepatoprotective and antioxidant effects in hepatocellular carcinoma models. KFP …

[HTML][HTML] Inhibition of PI3K/Akt/mTOR pathway by apigenin induces apoptosis and autophagy in hepatocellular carcinoma cells

J Yang, C Pi, G Wang - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Apigenin is a dietary flavonoid with known antioxidant and antitumor effects against several
types of cancers by promoting cell death and inducing cell cycle arrest. Apigenin also …

[HTML][HTML] Inhibitory effects of apigenin on the growth of gastric carcinoma SGC-7901 cells

K Wu, LH Yuan, W Xia - World Journal of Gastroenterology: WJG, 2005 - ncbi.nlm.nih.gov
AIM: To explore the growth inhibition and apoptosis-inducing effect of apigenin on human
gastric carcinoma SGC-7901 cells. METHODS: The effects of apigenin on the growth, clone …

[HTML][HTML] Doxorubicin and varlitinib delivery by functionalized gold nanoparticles against human pancreatic adenocarcinoma

SC Coelho, DP Reis, MC Pereira, MAN Coelho - Pharmaceutics, 2019 - mdpi.com
The aim of this study was to develop drug delivery nanosystems based on pegylated gold
nanoparticles (PEGAuNPs) for a combination against pancreatic cancer cells. Doxorubicin …

[HTML][HTML] Silver nanoparticles induce HePG-2 cells apoptosis through ROS-mediated signaling pathways

B Zhu, Y Li, Z Lin, M Zhao, T Xu, C Wang… - Nanoscale research …, 2016 - Springer
Recently, silver nanoparticles (AgNPs) have been shown to provide a novel approach to
overcome tumors, especially those of hepatocarcinoma. However, the anticancer …

Inhibition effects of gold nanoparticles on proliferation and migration in hepatic carcinoma-conditioned HUVECs

Y Pan, Q Wu, R Liu, M Shao, J Pi, X Zhao… - Bioorganic & medicinal …, 2014 - Elsevier
Tumor angiogenesis is a complicated process based upon a sequence of interactions
between tumor and vessel endothelial cells. Tumor conditioned medium has been widely …

Enhanced anti-tumor effect of combination therapy with gemcitabine and apigenin in pancreatic cancer

SH Lee, JK Ryu, KY Lee, SM Woo, JK Park, JW Yoo… - Cancer letters, 2008 - Elsevier
Apigenin is a dietary flavonoid possessing therapeutic potential against cancers. This study
was designed to investigate whether combination therapy with gemcitabine and apigenin …

[HTML][HTML] Oral administration of apigenin inhibits metastasis through AKT/P70S6K1/MMP-9 pathway in orthotopic ovarian tumor model

J He, Q Xu, M Wang, C Li, X Qian, Z Shi, LZ Liu… - International journal of …, 2012 - mdpi.com
Apigenin, a flavonoid commonly present in the daily diet, is known for its potential anti-tumor
properties. However, the effect of apigenin via oral administration on tumor growth and …