Description This expert review was commissioned and approved by the AGA Institute
Clinical Practice Updates Committee and the AGA Governing Board to provide timely …

The complex coagulation defect secondary to chronic liver disease is considered
responsible for the bleeding problems that often are associated with the disease …

Patients with acute and chronic liver disease frequently acquire unique changes in
haemodynamic and haemostatic pathways that may result in life-threatening bleeding and …

The human hemostasis system is complex and poorly understood after decades of intense
scientific study. Despite multiple defects in routine coagulation laboratory studies in patients …

Methods This document presents the official recommendations of the American
Gastroenterological Association Institute (AGA) on the management of coagulation disorders …

The state of clinical art of the coagulopathy of cirrhosis changed considerably over the last
decade. Until 2005, cirrhosis was considered as the epitome of the hemorrhagic …

The clotting process is a dynamic array of multiple processes which can be described in four
phases: platelet plug initiation and formation, clotting process propagation by the …

Epidemiological and laboratory studies performed in the last decades have changed our
understanding of coagulopathy in cirrhosis, from a condition at increased risk of …

Background The coagulopathy in cirrhosis is associated with thrombosis and bleeding.
Objectives To gain better insights into the coagulopathy in patients with cirrhosis, we …

The liver plays a crucial role in coagulation cascade. Global hemostatic process is
profoundly influenced by the presence of liver disease and its complications. Patients with …