Longer dinucleotide repeat polymorphism in matrix metalloproteinase-9 (MMP-9) gene promoter which correlates with higher HTLV-I Tax mediated transcriptional …

D Kodama, M Saito, W Matsumoto, AH Sabouri… - Journal of …, 2004 - Elsevier
Matrix metalloproteinase-9 (MMP-9) has been reported to be expressed in various
inflammatory disorders including human T cell lymphotropic virus type I (HTLV-I) associated …

Induction of CC-chemokines with antiviral function in macrophages by the human T lymphotropic virus type 2 transactivating protein, Tax2

G Balistrieri, CS Barrios, L Castillo… - Viral …, 2013 - liebertpub.com
Recent data provide evidence that co-infection with human immunodeficiency virus type 1
(HIV-1) and human T lymphotropic virus type 2 (HTLV-2) delays progression to AIDS …

Neuroimmunological aspects of human T cell leukemia virus type 1-associated myelopathy/tropical spastic paraparesis

M Saito - Journal of neurovirology, 2014 - Springer
Human T cell leukemia virus type 1 (HTLV-1) is a replicationcompetent human retrovirus
associated with two distinct types of disease: a malignancy of mature CD4+ T cells called …

Mediators of central nervous system damage during the progression of human T-cell leukemia type I-associated myelopathy/tropical spastic paraparesis

K Barmak, EW Harhaj, B Wigdahl - Journal of neurovirology, 2003 - Springer
Human T-cell leukemia virus type I (HTLV-I)-associated myelopathy/tropical spastic
paraparesis (HAM/TSP) represents one of the most devastating diseases associated with …

CC Chemokine Ligand 3 (CCL3) Regulates CD8+-T-Cell Effector Function and Migration following Viral Infection

MJ Trifilo, CC Bergmann, WA Kuziel, TE Lane - Journal of virology, 2003 - Am Soc Microbiol
Chemokines induce the directional migration of targeted populations of leukocytes during
periods of inflammation. Moreover, these molecules also regulate T-cell activation and …

HTLV-1 evades type I interferon antiviral signaling by inducing the suppressor of cytokine signaling 1 (SOCS1)

S Oliere, E Hernandez, A Lezin, M Arguello… - PLoS …, 2010 - journals.plos.org
Human T cell leukemia virus type 1 (HTLV-1) is the etiologic agent of Adult T cell Leukemia
(ATL) and the neurological disorder HTLV-1-associated myelopathy/tropical spastic …

Ciclosporin A proof of concept study in patients with active, progressive HTLV-1 associated myelopathy/tropical spastic paraparesis

F Martin, H Castro, C Gabriel, A Adonis… - PLoS neglected …, 2012 - journals.plos.org
Introduction Patients with HTLV-1-associated myelopathy/tropical spastic paraparesis
(HAM/TSP) become progressively impaired, with chronic pain, immobility and bladder …

Homeostatic chemokines CCL19 and CCL21 promote inflammation in human immunodeficiency virus-infected patients with ongoing viral replication

JK Damås, L Landrø, B Fevang… - Clinical & …, 2009 - academic.oup.com
CCL19 and CCL21 and their receptor CCR7 are expressed constitutively within lymphoid
organs, regulating lymphocyte homing. Recent studies suggest that these chemokines may …

Reduced Foxp3 expression with increased cytomegalovirus-specific CTL in HTLV-I-associated myelopathy

D Hayashi, R Kubota, N Takenouchi, Y Tanaka… - Journal of …, 2008 - Elsevier
Human T-lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic
paraparesis (HAM/TSP) patients show high immune responses to HTLV-I. However, it is …

Increased HTLV Type 1 Tax Specific CD8+ Cells in HTLV Type 1-Asociated Myelopathy/Tropical Spastic Paraparesis: Correlation with HTLV Type 1 Proviral Load

R Kubota, M Nagai, T Kawanishi, M Osame… - AIDS research and …, 2000 - liebertpub.com
Less than 1% of individuals infected with the human T lymphotropic virus type 1 (HTLV-1)
develop an inflammatory neurological disorder, termed HTLV-1-associated …