No-reflow phenomenon. A new target for therapy of acute myocardial infarction independent of myocardial infarct size

RA Kloner, W Dai, SL Hale - Journal of Cardiovascular …, 2018 - journals.sagepub.com
The no-reflow phenomenon is a failure to reperfuse portions of previously ischemic tissue
when patency of the large arteries perfusing an organ has been reestablished. This …

No-reflow phenomenon: maintaining vascular integrity

RA Kloner - Journal of cardiovascular pharmacology and …, 2011 - journals.sagepub.com
The no-reflow phenomenon relates to the inability to reperfuse regions of the myocardium
after ischemia, despite removal of the large epicardial coronary artery occlusion. The …

No-reflow: a heterogeneous clinical phenomenon with multiple therapeutic strategies

L Galiuto, F Crea - Current pharmaceutical design, 2006 - ingentaconnect.com
Previously defined as a shotcoming to achieve uniform intramyocardial reperfusion after
prolonged but reversible coronary occlusion, only recently has no-reflow phenomenon been …

No-reflow phenomenon and prognosis in patients with acute myocardial infarction

H Ito - Nature clinical practice Cardiovascular medicine, 2006 - nature.com
The rapid restoration of coronary flow to the jeopardized myocardium has become an
essential part of therapy after acute myocardial infarction. Despite an open infarct-related …

No-reflow phenomenon in the heart and brain

RA Kloner, KS King… - American Journal of …, 2018 - journals.physiology.org
The no-reflow phenomenon refers to the observation that when an organ is made ischemic
by occlusion of a large artery supplying it, restoration of patency in that artery does not …

Management of the no-reflow phenomenon

MJ Butler, W Chan, AJ Taylor, AM Dart… - Pharmacology & …, 2011 - Elsevier
The lack of reperfusion of myocardium after prolonged ischaemia that may occur despite
opening of the infarct-related artery is termed “no reflow”. No reflow or slow flow occurs in 3 …

[PDF][PDF] No reflow revisited

RA Kloner - J Am Coll Cardiol, 1989 - core.ac.uk
The no reflow phenomenon. This term refers to the inability to reperfuse myocardial tissue
after removal of a coronary artery occlusion (1). This phenomenon occurs not only in cardiac …

Microvascular alterations after temporary coronary artery occlusion: the no-reflow phenomenon

T Reffemann, RA Kloner - Journal of cardiovascular …, 2004 - journals.sagepub.com
In experimental models of temporary coronary artery occlusion, tissue perfusion at the
microvascular level remains incomplete even after patency of the infarct-related epicardial …

[PDF][PDF] The coronary no-reflow phenomenon: a review of mechanisms and therapies

E Eeckhout, MJ Kern - European heart journal, 2001 - doc.rero.ch
The phenomenon of no-reflow is defined as inadequate myocardial perfusion through a
given segment of the coronary circulation without angiographic evidence of mechanical …

[PDF][PDF] Early and late angiographic findings of the “no-reflow” phenomenon following direct angioplasty as primary treatment for acute myocardial infarction

H Feld, E Lichstein, J Schachter, J Shani - American Heart Journal, 1992 - academia.edu
The “no reflow phenomenon” is a well recognized consequence of reperfusion after
ischemia. l The term refers to the inability to reperfuse myocardial tissue despite removal of …