α‐linolenic acid interconversion is sufficient as a source of longer chain ω‐3 polyunsaturated fatty acids in humans: An opinion
GC Burdge - Lipids, 2022 - Wiley Online Library
Abstract α‐linolenic acid (αLNA) conversion into the functionally important ω‐3
polyunsaturated fatty acids (PUFA), eicosapentaenoic acid (EPA), and docosahexaenoic …
polyunsaturated fatty acids (PUFA), eicosapentaenoic acid (EPA), and docosahexaenoic …
α‐Linolenic acid metabolism in adult humans: the effects of gender and age on conversion to longer‐chain polyunsaturated fatty acids
GC Burdge, PC Calder - European Journal of Lipid Science …, 2005 - Wiley Online Library
This review summarises and evaluates current knowledge of α‐linolenic acid (αLNA)
metabolism in adult humans. The principal biological role of αLNA appears to be as a …
metabolism in adult humans. The principal biological role of αLNA appears to be as a …
Estimated conversion of α‐linolenic acid to long chain n‐3 polyunsaturated fatty acids is greater than expected in non fish‐eating vegetarians and non fish‐eating …
AA Welch, SA Bingham, KT Khaw - Journal of Human Nutrition …, 2008 - Wiley Online Library
Background: It is believed that n‐3 polyunsaturated fatty acid (PUFA) status is important for
cardiovascular health. However, the major sources of the essential dietary PUFA …
cardiovascular health. However, the major sources of the essential dietary PUFA …
Extremely limited synthesis of long chain polyunsaturates in adults: implications for their dietary essentiality and use as supplements
M Plourde, SC Cunnane - Applied physiology, nutrition, and …, 2007 - cdnsciencepub.com
There is considerable interest in the potential impact of several polyunsaturated fatty acids
(PUFAs) in mitigating the significant morbidity and mortality caused by degenerative …
(PUFAs) in mitigating the significant morbidity and mortality caused by degenerative …
Increased dietary α-linolenic acid has sex-specific effects upon eicosapentaenoic acid status in humans: re-examination of data from a randomised, placebo …
CE Childs, S Kew, YE Finnegan, AM Minihane… - Nutrition journal, 2014 - Springer
Background There is a metabolic pathway by which mammals can convert the omega-3 (n-
3) essential fatty acid α-linolenic acid (ALA) into longer-chain n-3 polyunsaturated fatty acids …
3) essential fatty acid α-linolenic acid (ALA) into longer-chain n-3 polyunsaturated fatty acids …
Are all n-3 polyunsaturated fatty acids created equal?
BM Anderson, DWL Ma - Lipids in health and Disease, 2009 - Springer
N-3 Polyunsaturated fatty acids have been shown to have potential beneficial effects for
chronic diseases including cancer, insulin resistance and cardiovascular disease …
chronic diseases including cancer, insulin resistance and cardiovascular disease …
Dietary α-linolenic acid and health-related outcomes: a metabolic perspective
GC Burdge, PC Calder - Nutrition research reviews, 2006 - cambridge.org
α-Linolenic acid (αLNA; 18: 3n-3) is essential in the human diet, probably because it is the
substrate for the synthesis of longer-chain, more unsaturated n-3 fatty acids, principally EPA …
substrate for the synthesis of longer-chain, more unsaturated n-3 fatty acids, principally EPA …
Alpha-linolenic acid and its conversion to longer chain n− 3 fatty acids: Benefits for human health and a role in maintaining tissue n− 3 fatty acid levels
G Barceló-Coblijn, EJ Murphy - Progress in lipid research, 2009 - Elsevier
There is little doubt regarding the essential nature of alpha-linolenic acid (ALA), yet the
capacity of dietary ALA to maintain adequate tissue levels of long chain n− 3 fatty acids …
capacity of dietary ALA to maintain adequate tissue levels of long chain n− 3 fatty acids …
Conversion of -linolenic acid to longer-chain polyunsaturated fatty acids in human adults
GC Burdge, PC Calder - Reproduction Nutrition Development, 2005 - rnd.edpsciences.org
The principal biological role of $\alpha $-linolenic acid ($\alpha $ LNA; 18: 3n-3) appears to
be as a precursor for the synthesis of longer chain n-3 polyunsaturated fatty acids (PUFA) …
be as a precursor for the synthesis of longer chain n-3 polyunsaturated fatty acids (PUFA) …
[PDF][PDF] The metabolic fate of alpha linolenic acid (ALA)
L Gillingham - IHP Mag, 2013 - cn.dpointernational.com
EPA and DHA possess important physiological and biological properties in human health
and development; however, it is alpha-linolenic acid (ALA) that is classified as the essential …
and development; however, it is alpha-linolenic acid (ALA) that is classified as the essential …