Acute kidney injury is common, with~ 13 million cases and 1.7 million deaths/year
worldwide. A major cause is renal ischaemia, typically following cardiac surgery, renal …

Chronic hypoxia likely plays a pivotal role in chronic renal disease, but the specifics of its
involvement remain unclear. To elucidate how chronic hypoxia occurs and whether hypoxia …

BACKGROUND: Hemorrhagic shock (HS) with conventional resuscitation (CR)(HSCR)
primes neurophils and modulates leukocyte (WBC)–endothelium interaction as part of an …

Role of medullary blood flow in the pathogenesis of renal is... : Current Opinion in
Nephrology and Hypertension Role of medullary blood flow in the pathogenesis of renal …

We report on the renal function and regional extravasation of albumin-bound Evans blue
dye (EB) in the kidneys of anesthetized dogs following 30 min occlusion of the left renal …

Compensated heart failure predisposes to outer medullary tubular injury: Studies in rats.
Background Heart failure (HF) is considered a putative factor predisposing to acute renal …

Purpose We recently observed that 30 min of bilateral renal arterial, venous, or pedicle
occlusion with 2-h reperfusion differentially induced acute kidney injury (AKI), which was …

Background Ischemia/reperfusion-induced polymorphonuclear neutrophil leukocyte (PMN)
adhesion and extravasation are pivotal for the development of postinjury multiple organ …

Renal congestion is caused by elevated central venous pressure (CVP), and decreases
glomerular filtration in patients with congestive heart failure. Since real-time contrast …

Background: We hypothesized that chronic renal parenchymal disease may predispose to
acute renal failure (ARF), facilitating the induction of hypoxic medullary tubular injury …