The aim of this study was to investigate the relationship between osteoporosis and
osteoarthritis by analyzing the DNA methylation in osteoporosis and osteoarthritis. The …

Objective To determine genome‐wide methylation profiles of bone from patients with hip
osteoarthritis (OA) and those with osteoporotic (OP) hip fractures. Methods Trabecular bone …

DNA methylation is one of the most studied epigenetic mechanisms that play a pivotal role in
regulating gene expression. The epigenetic component is strongly involved in aging-bone …

Background: Primary Osteoarthritis (OA) is a multifactorial disease in which genetic factors
are strongly associated with its development; however, recently it has been observed that …

Osteoporosis is characterized by systemic microarchitecture impairment and bone loss,
which ultimately lead to fragility fractures. This disease is most common in older people …

Background Researches indicate that epigenetics was involved in osteoarthritis (OA). The
purpose of this study was to describe the alterations of DNA methylation in hip and knee OA …

Osteoporosis is one of the most common age‐related progressive bone diseases in elderly
people. Approximately one in three women and one in five men are predisposed to …

Objectives To investigate abnormally methylated–differentially expressed genes (DEGs) and
their related pathways in osteoarthritis (OA) by comprehensive bioinformatic analysis …

Osteoporosis is one of the most common metabolic skeletal diseases, which affects more
than 200 million people worldwide, especially elderly and postmenopausal women. One of …

DNA methylation in eukaryotes invokes heritable alterations of the of the cytosine base in
DNA without changing the underlying genomic DNA sequence. DNA methylationmay be …