Single-cell RNA sequencing revealed a 3-gene panel predicted the diagnosis and prognosis of thyroid papillary carcinoma and associated with tumor immune …

Z Chen, Y Wang, D Li, Y Le, Y Han, L Jia, C Yan… - Frontiers in …, 2022 - frontiersin.org
Objective The objective of this research was to screen prognostic related genes of thyroid
papillary carcinoma (PTC) by single-cell RNA sequencing (scRNA-seq), to construct the …

Integrated analysis of tumor microenvironment features to establish a diagnostic model for papillary thyroid cancer using bulk and single-cell RNA sequencing …

Y Wang, W Song, Y Li, Z Liu, K Zhao, L Jia… - Journal of Cancer …, 2023 - Springer
Background Characterizing tumor microenvironment using single-cell RNA sequencing has
been a promising strategy for cancer diagnosis and treatment. However, a few studies have …

Single‐cell transcriptomic landscape reveals the differences in cell differentiation and immune microenvironment of papillary thyroid carcinoma between genders

M Peng, G Wei, Y Zhang, H Li, Y Lai, Y Guo, Y Chen… - Cell & bioscience, 2021 - Springer
Background Papillary thyroid carcinoma (PTC) is the main pathological type of thyroid
carcinoma (TC). Gender is a prominent background parameter for patients with PTC. Here …

[HTML][HTML] Transcriptomic analysis of papillary thyroid cancer: a focus on immune-subtyping, oncogenic fusion, and recurrence

SJ Park, YE Kang, JH Kim, JL Park… - Clinical and …, 2022 - synapse.koreamed.org
Objectives Thyroid cancer is the most common endocrine tumor, with rapidly increasing
incidence worldwide. However, its transcriptomic characteristics associated with …

[HTML][HTML] Integration of scRNA and bulk RNA-sequence to construct the 5-gene molecular prognostic model based on the heterogeneity of thyroid carcinoma …

Z Ni, S Cong, H Li, J Liu, Q Zhang, C Wei… - Acta Biochimica et …, 2024 - ncbi.nlm.nih.gov
Thyroid cancer (TC) is a kind of cancer with high heterogeneity, which leads to significant
difference in prognosis. The prognostic molecular processes are not well understood …

Prediction biomarkers associated with lymph node metastasis and prognosis were identified in papillary thyroid carcinoma via integrated bioinformatics analysis

S Gan, R Ye, Y Ha, Y Xiong, R Li, X Di… - … chemistry & high …, 2021 - ingentaconnect.com
Background: Prediction biomarkers associated with prognosis and lymph node metastasis
(LNM) in papillary thyroid carcinoma (PTC) are needed to facilitate clinicians in choosing …

Papillary thyroid carcinoma landscape and its immunological link with hashimoto thyroiditis at single-cell resolution

J Pan, F Ye, C Yu, Q Zhu, J Li, Y Zhang… - Frontiers in Cell and …, 2021 - frontiersin.org
The tumor microenvironment heterogeneity of papillary thyroid cancer (PTC) is poorly
characterized. The relationship between PTC and Hashimoto thyroiditis (HT) is also in …

Key molecules associated with thyroid carcinoma prognosis: A study based on transcriptome sequencing and GEO datasets

M Bai, S Ke, H Yu, Y Xu, Y Yu, S Lu, C Wang… - Frontiers in …, 2022 - frontiersin.org
Background Thyroid carcinoma (THCA) has a low mortality rate, but its incidence has been
rising over the years. We need to pay attention to its progression and prognosis. In this …

Single-cell transcriptome analysis reveals inter-tumor heterogeneity in bilateral papillary thyroid carcinoma

T Wang, J Shi, L Li, X Zhou, H Zhang, X Zhang… - Frontiers in …, 2022 - frontiersin.org
Background The tumor microenvironment (TME) plays a pivotal role in cancer progression in
papillary thyroid carcinoma (PTC), yet the composition and the phenotype of cells within the …

[HTML][HTML] Receptor–ligand pair typing and prognostic risk model for papillary thyroid carcinoma based on single-cell sequencing

ZX Cao, X Weng, JS Huang, X Long - Frontiers in Immunology, 2022 - frontiersin.org
The papillary thyroid carcinoma (PTC) microenvironment consists of various cancer and
surrounding cells, and the communication between them is mainly performed through ligand …