Urine output is widely used as a criterion for the diagnosis of AKI. Although several potential
mechanisms of septic AKI have been identified, regulation of urine flow after glomerular …

Sustained oliguria during fluid resuscitation represents a perplexing problem in patients
undergoing therapy for septic acute kidney injury. Here, we tested whether …

The acute renal failure associated with septic shock is associated with a high mortality
despite dialytic therapies. Endotoxemia leads to marked changes in the distribution of …

Endotoxins (lipopolysaccharides; LPS) are known to cause multiple organ failure, including
renal dysfunction. The present report elucidates LPS distribution and effect on renal …

Purpose To study the role of renal hypoperfusion in development of renal microcirculatory
dysfunction in endotoxemic rats. Methods Rats were randomized into four groups: a sham …

Acute kidney injury (AKI) remains a frequent and serious complication of human sepsis that
contributes significantly to mortality. For better understanding of the development of AKI …

Acute kidney injury (AKI) contributes greatly to morbidity and mortality in critically ill adults
and children. Patients with AKI who subsequently develop lung injury are known to suffer …

Acute renal failure (ARF) is a frequent and serious complication of endotoxemia caused by
lipopolysaccharide (LPS) and contributes significantly to mortality. The present studies were …

Renal insufficiency is a common and severe complication of sepsis, and the development of
kidney dysfunction increases morbidity and mortality in septic patients. Sepsis is associated …

Endotoxemia (LPS) can exacerbate ischemic tubular injury and acute renal failure (ARF).
The present study tested the following hypothesis: that acute ischemic damage sensitizes …