Lithium is abundantly administered against bipolar disorder. On the other hand, the lithium-
induced renal injury is a clinical complication which commonly reveals as drug-induced …

Long-term lithium treatment was associated with chronic kidney disease and renal failure
although the underlying pathogenic mechanisms are not certainty known. The aim of this …

Lithium preparations are commonly used drug in treating mental disorders and bipolar
diseases, but metal's cytotoxic mechanisms have not yet been completely understood. In this …

Lithium (Li+) is prescribed against a wide range of neurological disorders. Besides its
excellent therapeutic properties, there are several adverse effects associated with Li+. The …

The present work was aimed at studying the effects of a subchronic lithium treatment on rat
liver and kidneys, paying attention to the relationship between lithium toxicity, oxidative …

Lithium (Li) is a widely-used medication for the treatment of patients with bipolar disorder. Li
causes different complications. One of the most important adverse effects of Li is …

Lithium has been a valuable treatment for bipolar affective disorders for decades. Clinical
use of lithium, however, has been problematic due to its narrow therapeutic index and …

Lithium carbonate used in the long-term treatment of manic-depressive illness has been
reported to lead to progressive renal impairment in rats and humans. Caffeic acid phenethyl …

Objective This review is aimed at summarizing the information available in the literature
regarding the impact of lithium on renal structure and function, the prevalence of renal …

Background Despite lithium being the most efficacious treatment for bipolar disorder, its use
has been decreasing at least in part due to concerns about its potential to cause significant …