Ischemic stroke, caused by a lack of blood supply in brain tissues, is the third leading cause
of human death and disability worldwide, and usually results in sensory and motor …

Cerebral ischemia is one of the most devastating brain injuries and a primary cause of
acquired and persistent disability worldwide. Despite ongoing therapeutic interventions at …

Stroke constitutes the second leading cause of death and a major cause of disability
worldwide. Stroke is normally classified as either ischemic or hemorrhagic stroke (HS) …

Autophagy is a strictly regulated process that degrades and recycles long-lived or misfolded
proteins and damaged organelles for the maintenance of energy and function homeostasis …

Autophagy is a self-eating cellular catabolic pathway, through which long-lived proteins,
damaged organelles and misfolded proteins are degraded and recycled for the …

Stroke is a leading cause of mortality and morbidity worldwide. Understanding the
underlying mechanisms is important for developing effective therapies for treating stroke …

Cerebral ischemia is a severe outcome that could cause cognitive and motor dysfunction,
neurodegenerative diseases and even acute death. Although the existence of autophagy in …

Autophagy is an important biological mechanism involved in the regulation of numerous
fundamental cellular processes that are mainly associated with cellular growth and …

Although many attempts have been made, stroke treatment options are still extremely limited
and brain ischemia remains the leading cause of death and disability worldwide. Two major …

Ischemic stroke is a highly disabling and potentially fatal disease. After ischemic stroke,
autophagy plays a key regulatory role as an intracellular catabolic pathway for misfolded …