Vitamin D deficiency aggravates nephrotoxicity, hypertension and dyslipidemia caused by tenofovir: role of oxidative stress and renin-angiotensin system
D Canale, AC de Bragança, JG Gonçalves… - PloS one, 2014 - journals.plos.org
Vitamin D deficiency (VDD) is prevalent among HIV-infected individuals. Vitamin D has been
associated with renal and cardiovascular diseases because of its effects on oxidative stress …
associated with renal and cardiovascular diseases because of its effects on oxidative stress …
Tenofovir-induced nephrotoxicity: incidence, mechanism, risk factors, prognosis and proposed agents for prevention
A Jafari, H Khalili, S Dashti-Khavidaki - European journal of clinical …, 2014 - Springer
Objective In this study, data regarding epidemiology, risk factors, pathogenesis and outcome
of tenofovir-induced nephrotoxicity will be reviewed, and current and future approaches for …
of tenofovir-induced nephrotoxicity will be reviewed, and current and future approaches for …
Preclinical efficacy of melatonin in the amelioration of tenofovir nephrotoxicity by the attenuation of oxidative stress, nitrosative stress and inflammation in rats
H Ramamoorthy, P Abraham, B Isaac - Journal of basic and clinical …, 2014 - degruyter.com
Background: Nephrotoxicity is a dose-limiting side effect of long-term use of tenofovir, a
reverse transcriptase inhibitor that is used for the treatment of human immunodeficiency …
reverse transcriptase inhibitor that is used for the treatment of human immunodeficiency …
[HTML][HTML] Incidence and predictors of tenofovir disoproxil fumarate-induced renal impairment in HIV infected Nigerian patients
Methods This retrospective cohort analysis included patients aged≥ 16 years that initiated
ART between January 2008 and December 2011. Renal impairment, defined as glomerular …
ART between January 2008 and December 2011. Renal impairment, defined as glomerular …
Inadequate vitamin D exacerbates parathyroid hormone elevations in tenofovir users
KE Childs, SL Fishman, C Constable… - AIDS research and …, 2010 - liebertpub.com
Parathyroid hormone (PTH) elevations are associated with reduced bone mineral density
and adverse health outcomes and have been reported in patients with HIV infection. We …
and adverse health outcomes and have been reported in patients with HIV infection. We …
Tenofovir is associated with increased tubular proteinuria and asymptomatic renal tubular dysfunction in Ghana
Background HIV infection is associated with increased risk of renal dysfunction, including
tubular dysfunction (TD) related to antiretroviral therapy (ART). Tenofovir disoproxil fumarate …
tubular dysfunction (TD) related to antiretroviral therapy (ART). Tenofovir disoproxil fumarate …
Mitochondrial pathway of apoptosis and necrosis contribute to tenofovir disoproxil fumarate–induced renal damage in rats
H Ramamoorthy, P Abraham, B Isaac… - Human & …, 2019 - journals.sagepub.com
Tenofovir disoproxil fumarate (TDF) is currently the only nucleotide analogue reverse-
transcriptase inhibitor that is approved by the Food and Drug administration (FDA), USA, for …
transcriptase inhibitor that is approved by the Food and Drug administration (FDA), USA, for …
Cumulative exposure of TDF is associated with kidney tubulopathy whether it is currently used or discontinued
T Nishijima, Y Mutoh, Y Kawasaki, K Tomonari… - Aids, 2018 - journals.lww.com
Objective: Tenofovir disoproxil fumarate (TDF) increases the risk of kidney tubular
dysfunction (KTD). This study was conducted to elucidate whether KTD persists after …
dysfunction (KTD). This study was conducted to elucidate whether KTD persists after …
Incidence and risk factors for tenofovir-associated renal toxicity in HIV-infected patients
PR Quesada, LL Esteban, JR García… - International journal of …, 2015 - Springer
Background Since the beginning of highly active antiretroviral therapy utilization, the
association of renal impairment with treatment toxicity is more prevalent. Tenofovir disoproxil …
association of renal impairment with treatment toxicity is more prevalent. Tenofovir disoproxil …
Long-term exposure to tenofovir continuously decrease renal function in HIV-1-infected patients with low body weight: results from 10 years of follow-up
T Nishijima, Y Kawasaki, N Tanaka, D Mizushima… - Aids, 2014 - journals.lww.com
Objectives: To investigate the effect of long-term tenofovir disoproxil fumarate (TDF) use on
renal function, especially in patients with low body weight who are vulnerable to TDF …
renal function, especially in patients with low body weight who are vulnerable to TDF …