Platinum (Ⅳ) compounds which exert unique advantages as antitumor drugs, have aroused
wide attention of researchers in pharmaceutical area. A great deal of efforts have been …

The discovery of new types of anti-cancer agent is not always the result of large scale
screening or of working hypotheses which suggest that a particular chemical may have anti …

Six new platinum complexes of the formula [Pt (2, 2'-bipyndine)(amino acid)] n+, where n= 1
to 2 and amino acid is an anion of L-histidine, L-lysine, L-asparagine, L-phenylalanine, L …

An Editorial was published in the journal" Anti-Cancer Agents in Medicinal Chemistry",
Volume 7, No. 01, 2007, pp: 1-2 [1]. The guest editor is requesting an alteration in the name …

This article describes the prime role of anticancer drugs based on platinum in clinical
treatment, their limitations and side effects. The efforts to investigate the molecular …

The Aim: The purpose of our study to synthesis of [6-(((Z)-1, 5-dimethyl-2-phenyl-4-(((E)-4-
(pyridin-2-yl) benzylidene) amino)-1, 2-dihydro-3H-pyrazol-3-ylidene) amino)-3, 3-dimethyl …

This chapter will be devoted to discussion of the experimental techniques applied for both
analysis and characterization with special reference to the instrumentation involved. The …

Rosenberg et al discovered in the coordination complexes of platinum a new, novel type of
potential antitumor agent. Cisplatin [cis-dichlorodiammine platinum (II) 4 proved active …

A large body of novel platinum and palladium complexes, in both the cis-and trans-forms,
with various donor ligands, eg beta-carboline alkaloids, pyrazoles, DMSO …

Since the initi, al discovery by Rosenberg and Van Camp of potent anti-tumour activity in
certain platinum amine complexes, ave have been carrying out a programme of synthesis …