Background: The incidence and mortality rates of hepatocellular carcinoma (HCC) are
increasing worldwide. Therefore, there is an urgent need to elucidate the molecular drivers …

Abstract Background Embryonic Liver Fodrin (ELF) is an adaptor protein of transforming
growth factor (TGF-β) signaling cascade. Disruption of ELF results in mislocalization of …

Hepatocellular carcinoma is one leading cause of cancer-related death and surgical
resection is still one of the major curative therapies. Recently, there has been a major effort …

Background Aberrations in MYC underlie a large proportion of liver hepatocellular
carcinoma (LIHC) cases; however, MYC is difficult to target because of its undruggable …

Amplification of 8q23-qter is common in human hepatocellular carcinoma (HCC). c-myc, an
oncogene located on 8q24, may be important in hepatocarcinogenesis. The present study …

Objectives: c-myc is a transcription factor that regulates cell proliferation, differentiation, and
apoptosis. However, little is known about the clinical importance of c-myc mRNA expression …

Hepatocarcinogenesis is a multistage process in which precursor lesions progress into early
hepatocellular carcinomas (eHCC) by sequential accumulation of multiple genetic and …

The proto‐oncogene MYCN expression marked a cancer stem‐like cell population in
hepatocellular carcinoma (HCC) and served as a therapeutic target of acyclic retinoid …

Purpose In this study, we aimed to assess the association between MYBL2 expression/
transcription regulatory activity (TRA) and overall survival (OS) in patients with primary …

Introduction: Hepatocellular carcinoma (HCC) is a leading cause of cancer death worldwide
and recurrence rate after curative resection remains high. To improve HCC prognosis, novel …