The discovery that gut-microbiota plays a profound role in human health has opened a new
avenue of basic and clinical research. Application of ecological approaches where the …

Cardiovascular disease (CVD) remains the most common cause of death worldwide and
has become a public health concern. The proven notable risk factors for CVD are …

Although diet has long been known to contribute to the pathogenesis of cardiovascular
disease (CVD), research over the past decade has revealed an unexpected interplay …

A combinatory approach using metabolomics and gut microbiome analysis techniques was
performed to unravel the nature and specificity of metabolic profiles related to gut ecology in …

During the past decade, meta-omics approaches have revolutionized microbiology, allowing
for a cultivation-free assessment of the composition and functional properties of entire …

Background Recent studies in animal models have shown a link between ingestion of
dietary phosphatidylcholine (PC), choline, l-carnitine and cardiovascular risk. Intestinal …

Emerging evidence has linked the gut microbiome to human obesity. We performed a
metagenome-wide association study and serum metabolomics profiling in a cohort of lean …

A Western-style, high-fat diet promotes cardiovascular disease, in part because it is rich in
choline, which is converted to trimethylamine (TMA) by the gut microbiota. However, whether …

Trimethylamine N-oxide (TMAO), which is oxidized from trimethylamine (TMA) by hepatic
flavin-containing monooxygenases (FMOs), promotes the development of atherosclerosis …

Cardiovascular disease (CVD) is strongly associated with the gut microbiota and its
metabolites, including trimethylamine-N-oxide (TMAO), formed from metaorganismal …