Aims To describe the population pharmacokinetics (PK) and probability of target attainment
(PTA) of continuous infusion (CI) of meropenem in septic patients receiving renal …

Purpose Critically ill patients with preserved or increased renal function have been shown to
be at risk of underexposure to meropenem. Although many meropenem population …

Meropenem dosing in critically ill patients with septic shock and continuous renal
replacement therapy (CRRT) is complex, with the recommended maintenance doses being …

Introduction: The optimal meropenem dosing regimens in critically ill patients receiving
continuous renal replacement therapy (CRRT) based on pharmacokinetic and …

Background: The aim of this study was to conduct a population pharmacokinetic (PK)
analysis of meropenem and to explore the optimal dosing strategy for meropenem in …

Background The primary objective of this study was to develop a population
pharmacokinetic model of meropenem, based on the population of critically ill adult patients …

Purpose: Creatinine clearance (CCr) and pharmacokinetic parameters are markedly
affected by pathophysiological changes in patients with sepsis. However, only a few reports …

Abstract Background and Objectives Meropenem is frequently used for the treatment of
severe bacterial infections in critically ill patients. Because critically ill patients are more …

The optimal dosing regimen for meropenem in critically ill patients undergoing continuous
renal replacement therapy (CRRT) remains undefined due to small studied sample sizes …

Objectives The use of extended intermittent infusion (EII) or continuous infusion (CI) of
meropenem is recommended in intensive care unit (ICU) patients, but few data comparing …