Neuroendocrine neoplasms of lung, pancreas and gut: a morphology-based comparison

A Kasajima, G Klöppel - Endocrine-Related Cancer, 2020 - erc.bioscientifica.com
The bronchopulmonary (BP) and gastroenteropancreatic (GEP) organ systems harbor the
majority of the neuroendocrine neoplasms (NENs) of the body, comprising 20 and 70% of all …

Lung and digestive neuroendocrine neoplasms. From WHO classification to biomarker screening: Which perspectives?

JY Scoazec - Annales d'Endocrinologie, 2019 - Elsevier
The recent classifications of lung and digestive neuroendocrine neoplasms (NENs) make a
fundamental distinction between well-and poorly-differentiated neoplasms. Well …

Neuroendocrine neoplasms of the gastroenteropancreatic system: pathology and classification

M Anlauf - Hormone and metabolic research, 2011 - thieme-connect.com
Neuroendocrine neoplasms (NEN) appear homogeneous in terms of morphology, but
constitute a very heterogeneous group of tumors in terms of biological and clinical features …

Neuroendocrine neoplasms of the lung and gastrointestinal system: convergent biology and a path to better therapies

K Kawasaki, N Rekhtman… - Nature Reviews …, 2023 - nature.com
Neuroendocrine neoplasms (NENs) can develop in almost any organ and span a spectrum
from well-differentiated and indolent neuroendocrine tumours (NETs) to poorly differentiated …

Update on histological reporting changes in neuroendocrine neoplasms

K Bräutigam, A Rodriguez-Calero, C Kim-Fuchs… - Current Oncology …, 2021 - Springer
Abstract Purpose of Review Classification and nomenclature of neuroendocrine neoplasms
(NEN) have frequently changed over the last years. These changes reflect both increasing …

Tumour biology and histopathology of neuroendocrine tumours

G Klöppel - Best practice & research Clinical endocrinology & …, 2007 - Elsevier
The tumours of the disseminated/diffuse neuroendocrine cell system are a group of
neoplasms sharing uniformly appearing cells which differ from each other in their biology …

Molecular Classification of Gastrointestinal and Pancreatic Neuroendocrine Neoplasms: Are We Ready for That?

S Uccella - Endocrine Pathology, 2024 - Springer
In the last two decades, the increasing availability of technologies for molecular analyses
has allowed an insight in the genomic alterations of neuroendocrine neoplasms (NEN) of …

Genomics of high-grade neuroendocrine neoplasms: well-differentiated neuroendocrine tumor with high-grade features (G3 NET) and neuroendocrine carcinomas …

S Uccella, S La Rosa, J Metovic, D Marchiori… - Endocrine …, 2021 - Springer
High-grade neuroendocrine neoplasms (HG-NENs) are clinically aggressive diseases, the
classification of which has recently been redefined. They now include both poorly …

Genetics and epigenetics of gastroenteropancreatic neuroendocrine neoplasms

A Mafficini, A Scarpa - Endocrine reviews, 2019 - academic.oup.com
Gastroenteropancreatic (GEP) neuroendocrine neoplasms (NENs) are heterogeneous
regarding site of origin, biological behavior, and malignant potential. There has been a rapid …

Genetic and epigenetic drivers of neuroendocrine tumours (NET)

A Di Domenico, T Wiedmer, I Marinoni… - Endocrine-related …, 2017 - erc.bioscientifica.com
Neuroendocrine tumours (NET) of the gastrointestinal tract and the lung are a rare and
heterogeneous group of tumours. The molecular characterization and the clinical …