Correlation of peripheral Th17 cells and Th17-associated cytokines to the severity of carotid artery plaque and its clinical implication

Z Liu, F Lu, H Pan, Y Zhao, S Wang, S Sun, J Li, X Hu… - Atherosclerosis, 2012 - Elsevier
OBJECTIVE: Atherosclerosis is a chronic inflammatory disease regulated by T lymphocyte
subsets. Th17 cells reportedly play important roles in the development of inflammatory and …

Regulatory T CD4+ CD25+ lymphocytes increase in symptomatic carotid artery stenosis

F Del Porto, N Cifani, M Proietta, S Perrotta… - Annals of …, 2017 - Taylor & Francis
Background: Atherosclerosis is a multifactorial disease characterized by an immune-
inflammatory remodeling of the arterial wall. Treg and Th17 subpopulations are detectable …

Increased Th17 cells in coronary artery disease are associated with neutrophilic inflammation

Z Wang, J Lee, Y Zhang, H Wang, X Liu… - Scandinavian …, 2011 - Taylor & Francis
Objective. Atherosclerosis is a progressive disease characterized by a series of
inflammatory responses in the large and medium arteries. Th17 cells, a distinct T cell …

Increased circulating Th17 cells, serum IL‐17A, and IL‐23 in Takayasu arteritis

DP Misra, S Chaurasia, R Misra - Autoimmune diseases, 2016 - Wiley Online Library
Introduction. Th17, γδT, NK, and NKT cells in peripheral blood and serum IL‐17 and IL‐23 in
Takayasu arteritis (TA) were measured and correlated with disease activity. Methods. Th17 …

Increased Th17 cell frequency concomitant with decreased Foxp3+ Treg cell frequency in the peripheral circulation of patients with carotid artery plaques

Z Liu, L Wang, F Lu, H Pan, Y Zhao, S Wang… - Inflammation …, 2012 - Springer
Objective and design We investigated a possible imbalance between T helper (Th) 17 and
CD4+ CD25+ forkhead/winged helix transcription factor (Foxp3) T regulatory (Treg) cells in …

Detection of TCD4+ subsets in human carotid atheroma

RTD Oliveira, RM Silva, FH Teo, MF Mineiro… - Cytokine, 2013 - Elsevier
Activated TCD4+ cells are detected in human atherosclerotic plaques which indicate their
participation in disease progression and destabilization. Among these cells, IFN-γ-producing …

A critical function of Th17 proinflammatory cells in the development of atherosclerotic plaque in mice

Q Gao, Y Jiang, T Ma, F Zhu, F Gao… - The Journal of …, 2010 - journals.aai.org
Considerable evidence supports that the CD4+ T cell-mediated immune response
contributes to the development of atherosclerotic plaque. However, the effects of Th17 cells …

[HTML][HTML] The pleiotropic role of interleukin-17 in atherosclerosis

G Allam, A Abdel-Moneim, AM Gaber - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Atherosclerosis is the main cause of cardiovascular diseases (CVDs), which considers the
leading cause of mortality worldwide. Atherosclerosis is a chronic inflammatory condition of …

[HTML][HTML] Interleukin-17-Producing CD4+ T Cells Promote Inflammatory Response and Foster Disease Progression in Hyperlipidemic Patients and Atherosclerotic …

Y Wang, W Li, T Zhao, Y Zou, T Deng… - Frontiers in …, 2021 - frontiersin.org
Atherosclerosis is a chronic inflammatory disease. Interleukin-17-producing CD4+ T cells
(Th17 cells) play important roles in the progression of atherosclerosis. However, most of the …

The paradoxical role of IL-17 in atherosclerosis

F Gong, Z Liu, J Liu, P Zhou, Y Liu, X Lu - Cellular immunology, 2015 - Elsevier
Atherosclerosis is a chronic inflammatory disease mediated by innate and adaptive immune
responses. In recent years, CD4+ T cells (Th1, Th2, Treg, and Th17) have been increasingly …